Results 51 to 60 of about 107,391 (310)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Queer Sinophone Literature in Hong Kong: The Politics of Worldliness

open access: yes, 2023
Sinophone studies examines the dissemination of Sinitic-language communities and their lived histories and cultural expressions. In Visuality and Identity, Shu-mei Shih defines the Sinophone as “a network of places of cultural production outside China ...
Wong, Alvin K
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Ricardo Piglia: literatura, dinero, propiedad

open access: yesCuadernos LIRICO, 2019
Ricardo Piglia saw in the links between economics and literature an element that questions the modern idea of the autonomy of literature with respect to other social dynamics.
Eduardo Becerra
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

‘Importing’ the personal vote to maximise the party vote? ‘Parachute personalization’ in an intraparty preference electoral system [PDF]

open access: yes
This article seeks to contribute to the electoral and party politics debate in three main ways. The first is the claim that parachuting politicians into districts in which they have no prior connections is not a nomination practice that is the exclusive ...
Arter, David, Poyet, Corentin
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Selections from Varlık 1933-2008 (2008) Osman Deniztekin (ed.); Sabahattin Eyüboğlu (2008) The Blue and the Black, translated by Hughette Eyüboğlu and Lynne Saka; Bengisu Rona (2008) Orhan Kemal in Jail with Nazım Hikmet.

open access: yesEuropean Journal of Turkish Studies, 2010
This extended review of three recently published English translations of the works of intellectuals such as Nazım Hikmet, Orhan Kemal and Sabahattin Eyüboğlu shows how they emphasized the importance of freedom of thought, in a context that continually ...
Laurence Raw
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

The Politics of literature: Poland 1945-89

open access: yes, 1989
bookThis study explores the relationship between literature and politics. It asks what literature can tell us about politics, and it does so by exploring Polish literary-political culture in the years 1945-89.
Tighe, Carl
core  

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