Results 91 to 100 of about 16,681,036 (304)

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Production of Poly-L-Lactic Acid from L-Lactic Acid Isolated from Kitchen Waste Fermented Using Enterococcus Gallinarum Eb1 [PDF]

, 2006
Lactic acid (LA) has potential applications in the chemical and biodegradable plastics industries. The L-form LA monomer can be polymerized to polylactate, a degradable polymer with potential to substitute certain environmentally recalcitrant plastics.
Ooi, Kim Yng
core   +1 more source

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source

Polímeros biorreabsorvíveis como substrato para cultura de células e engenharia tecidual Bioreabsorbable polymers for cell culture substrate and tissue engineering

Polímeros, 2007
Biomateriais poliméricos são desenvolvidos para uso como substitutos de tecidos danificados e/ou estimular sua regeneração. Uma classe de biomateriais poliméricos são os biorreabsorvíveis, compostos que se decompõem tanto in vitro quanto in vivo.
Arnaldo R. Santos Jr, Maria Lucia F. Wada   +1 more
doaj   +1 more source

Robust poly(lactic acid) membranes improved by polysulfone-g-poly(lactic acid) copolymers for hemodialysis

, 2015
Poly(lactic acid) (PLA) is a sustainable membrane candidate for liquid separation and purification. However, the inherent brittleness restrains its practical application, especially for a porous membrane with thin thickness and high porosity.
Liu, Fu, Wang, Yunze, Xiong, Zhu, Wang, Linghui, Yu, Xuemin   +4 more
core  

Heating and Annealing Induced Structural Reorganization and Embrittlement of Solution-Crystallized Poly(l‑lactic acid)

, 2016
Heating and Annealing Induced Structural Reorganization and Embrittlement of Solution-Crystallized Poly(l‑lactic ...
Guorong Shan (1448014), Lili Han (1426681), Yongzhong Bao (1448008), Pengju Pan (1448005)   +3 more
core   +1 more source

Mesoscale Modeling and Experimental Study of Quercetin Organization as Nanoparticles in the Poly-lactic-co-glycolic Acid/Water System under Different Conditions

, 2020
To understand the nanoparticle formation of quercetin in the poly-lactic-co-glycolic acid/water system, a multiscale approach combining experimental, molecular, and mesoscale modelings was carried out.
Latifa Chebil (2263138), Latifa Chebil, Manel Slimane (8462559), Ibrahima Gaye (8462562), Mohamed Ghoul (2263144), Manel Slimane, Ibrahima Gaye, Mohamed Ghoul   +7 more
core   +1 more source

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Synthesis of ciprofloxacin-conjugated poly (L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation

International Journal of Nanomedicine, 2014
Sharad P Parwe, Priti N Chaudhari, Kavita K Mohite, Balaji S Selukar, Smita S Nande, Baijayantimala Garnaik Polymer Science and Engineering Division, National Chemical Laboratory, Pune, India Abstract: Ciprofloxacin was conjugated with polylactide (PLA)
Parwe SP, Chaudhari PN, Mohite KK, Selukar BS, Nande SS, Garnaik B   +5 more
doaj