Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao +12 more
wiley +1 more source
Induction and Stabilization of Peptide Alpha‐Helices on Silica Nanoparticles
Covalent docking turns silica nanoparticles (SNPs) into α‐helix‐stabilizing surfaces. Dynamic imine formation allows peptides with lysine residues aligned on one helical face to adapt to the surface before reduction locks the structure in place, while preserving the opposite face for functional recognition.
Fidel Lozano‐Elena +3 more
wiley +2 more sources
An electromagnetic manipulation system enhances magnetic field strength in the Z‐direction for 3D control of microrobots and nanoparticles. Featuring eight metal‐core coils and two air‐core coils arranged hemispherically, it ensures unimpeded workspace access and integrates imaging tools.
Nader Latifi Gharamaleki +4 more
wiley +1 more source
Bacillaceae serine proteases and Streptomyces epsilon-poly-L-lysine synergistically inactivate Caliciviridae by inhibiting RNA genome release. [PDF]
Yamamoto S +17 more
europepmc +1 more source
Phase Separation of Caboxylated Poly-L-Lysine
Supervisor:Dr.
openaire
Exploring the Conformational Landscape of Poly(l-lysine) Dendrimers Using Ion Mobility Mass Spectrometry. [PDF]
Benoit F +6 more
europepmc +1 more source
Cellular and Molecular Insights into the Divergence of Neural Stem Cells on Matrigel and Poly-l-lysine Interfaces. [PDF]
Wu C +10 more
europepmc +1 more source
In vitro and in vivo evaluation of a tetrazine-conjugated poly-L-lysine effector molecule labeled with astatine-211. [PDF]
Timperanza C +5 more
europepmc +1 more source
Development of Innovative Composite Nanofiber: Enhancing Polyamide-6 with ε-Poly-L-Lysine for Medical and Protective Textiles. [PDF]
Purandare S, Li R, Xiang C, Song G.
europepmc +1 more source
Composite Hydrogels with Rapid Self-Healing, Stretchable, Moldable and Antibacterial Properties Based on PVA/ε-Poly-l-lysine/Hyaluronic Acid. [PDF]
Sun N +5 more
europepmc +1 more source

