Poly(iminomethylenes). 10. Esterolytic catalysis by poly(carbylhistidine) and poly(carbylhistamine) [PDF]
AbstractThe catalytic activities in the hydrolysis of 4‐nitro‐ and 2,4‐dinitrophenyl acetate were determined for a polymer of 3‐(4‐imidazolyl)‐2‐isocyanopropanoic acid (1a) and of 2‐(4‐imidazolyl)‐1‐isocyanoethane (1b). A detailed kinetic analysis has been performed.
Eijk, J.M. van der +3 more
openaire +2 more sources
Fourth Moment Theorems for Markov Diffusion Generators [PDF]
Inspired by the insightful article arXiv:1210.7587, we revisit the Nualart-Peccati-criterion arXiv:math/0503598 (now known as the Fourth Moment Theorem) from the point of view of spectral theory of general Markov diffusion generators.
Azmoodeh, Ehsan +2 more
core
Stein's method, Malliavin calculus, Dirichlet forms and the fourth moment theorem
The fourth moment theorem provides error bounds of the order $\sqrt{{\mathbb E}(F^4) - 3}$ in the central limit theorem for elements $F$ of Wiener chaos of any order such that ${\mathbb E}(F^2) = 1$.
Chen, Louis H. Y., Poly, Guillaume
core +1 more source
Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Dunnett, Hannah +2 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Convergence in distribution norms in the CLT for non identical distributed random variables
We study the convergence in distribution norms in the Central Limit Theorem for non identical distributed random variables that is $$ \varepsilon_{n}(f):={\mathbb{E}}\Big(f\Big(\frac 1{\sqrt n}\sum_{i=1}^{n}Z_{i}\Big)\Big)-{\mathbb{E}}\big(f(G)\big ...
Bally, Vlad +2 more
core +4 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Freedom, warriors’ bond, legal book. The Lex Salica between Barbarian custom and Roman law
Salic Law, the most famous of the so-called barbarian leges, was both barbarian and roman. It was made during the 4th century for the Frankish military dependants (dediticii) and their families settled in the Extrema Galliae, the Far Gaul.
Jean-Pierre Poly
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

