Results 31 to 40 of about 759,541 (219)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Predicting the Kentucky Derby Winner! Sort of
Journal of Statistics Education, 2019 Through a series of explorations, this article will demonstrate how the Kentucky Derby winning times dataset provides various opportunities for introductory and advanced topics, from data processing to model building.
Beth Chance, Shea Reynolds
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
A uniaxial compression damage model for rockmass considering the crack deformation parameter
Shuiwen dizhi gongcheng dizhi, 2023 In order to accurately predict the effect of crack on the rockmass compression mechanical property such as strength and stiffness, a more reasonable compression damage model for the cracked rockmass is needed to be established.
Hongyan LIU +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Toolpath strategies and management to optimize energy consumption on 3-axis CNC milling machine
E3S Web of Conferences, 2018 CNC milling machine is a production machine which widely used to manufacture many kinds of products. In the process of milling machining, the time needed to produce a component must be as minimum as possible to minimize the costs and its impacts on the ...
Kiswanto Gandjar +2 more
doaj +1 more source
Applying means-end to hospitality hosts: a study of winery tasting rooms [PDF]
International Hospitality ReviewPurpose – The paper has a twofold purpose: (1) to test the application of means-end theory to providers of hospitality goods and services, and (2) to explore this question in the context of winery tasting rooms when they had a unique opportunity to ...
Terry Lease +3 more
doaj +1 more source
Freedom, warriors’ bond, legal book. The Lex Salica between Barbarian custom and Roman law
Clio@Themis, 2021 Salic Law, the most famous of the so-called barbarian leges, was both barbarian and roman. It was made during the 4th century for the Frankish military dependants (dediticii) and their families settled in the Extrema Galliae, the Far Gaul.
Jean-Pierre Poly
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source