Results 151 to 160 of about 25,360,752 (379)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, Volume 15, Issue 7, Page 1079-1089, July 2025.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, Volume 15, Issue 7, Page 1090-1102, July 2025.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Physikalisch-chemische Messungen an Poly-Methylphenylenen. (Vorläufige Mitteilung). [PDF]

, 1951
Robert Gehm, Lars Bjellerup, Inger Rubin, E. Saluste, R. Stjernholm, G. Ehrensvärd   +5 more
openalex   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

FEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian, Di Liu, Bing Liu, Yu Lan, Jie Zhou   +4 more
wiley   +1 more source

STUDIES ON THE OILINESS OF LIQUIDS. II. FRICTION COEFFICIENTS OF THE FILMS OF MONO-AND POLY-MOLECULAR LAYERS [PDF]

, 1936
Hideo Akamatu, Jitsusaburo Sameshima
openalex   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

A polypropylene mesh modified with poly-ε-caprolactone nanofibers in hernia repair: large animal experiment

International Journal of Nanomedicine, 2018
Barbora East,1,2 Martin Plencner,3,4 Martin Kralovic,1,3,5 Michala Rampichova,3 Vera Sovkova,1,3,5 Karolina Vocetkova,1,3,5 Martin Otahal,6,7 Zbynek Tonar,8,9 Yaroslav Kolinko,8,9 Evzen Amler,1,3,5 Jiri Hoch1,10 1Second Medical Faculty, Charles ...
East B, Plencner M, Kralovic M, Rampichova M, Sovkova V, Vocetkova K, Otahal M, Tonar Z, Kolinko Y, Amler E, Hoch J   +10 more
doaj  

THE USE OF THE SKIN TEST WITH THE TYPE SPECIFIC POLY-SACCHARIDES IN THE CONTROL OF SERUM DOSAGE IN PNEUMOCOCCAL PNEUMONIA [PDF]

, 1938
Colin M. MacLeod, Charles L. Hoagland, Paul B. Beeson   +2 more
openalex   +1 more source