Molecular Weight Distribution of Proteins Synthesized in Single, Identified Neurons of Aplysia [PDF]
Parietovisceral ganglia from Aplysia californica were incubated in medium containing leucine-3H. Single, identified nerve cell somas were isolated from the ganglia, and their proteins extracted and separated by electrophoresis on 5% SDS-polyacrylamide ...
Wilson, David L.
core +4 more sources
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki+4 more
wiley +1 more source
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican+7 more
wiley +1 more source
Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]
Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J.+3 more
core +2 more sources
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
Waste slurry is a major component of construction waste, and its resource utilization can effectively reduce its environmental impact. The effect of polyacrylamide (PAM) content and moisture content on the strength characteristics of PAM modified cement ...
Feng Guo, Jiabin Hu
doaj +1 more source
Polymer Hydrogels Based on Acrylic Acid and Acrylamide and Their Applications to Remove Cationic Dye of Basic Red 46 (BR 46) from Aqueous Solutions [PDF]
Hypothesis: The removal of dyes using polymers with different functional groups is of great concern in environmental applications. Polymeric adsorbents, particularly hydrogels, through formation of polymer complexes by electrostatic attraction and ...
Khadijeh Didehban+2 more
doaj +1 more source
Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells [PDF]
Affinity-purified antibodies and cDNA probes specific for the chicken erythrocyte anion transporter (also referred to as band 3) have been used to demonstrate that this protein is expressed in a highly cell- type-specific manner in the avian kidney ...
Cox, John V.+2 more
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Evaluation of Carbon Nanotubes and Polyacrylamide Binders for Cold Agglomeration in Iron Ore Sintering with High Proportions of Ultrafine Particles [PDF]
The influence of polyacrylamide and multi-wall carbon nanotubes as binders for the granulation process for iron ore sintering was investigated in conditions of high proportions of ultrafine (< 0.150 mm).
Arthur Felipe Lino Oliveira+3 more
doaj +1 more source