Results 41 to 50 of about 446,459 (290)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Rheological Properties of Weak Gel System Cross-Linked from Chromium Acetate and Polyacrylamide and Its Application in Enhanced Oil Recovery After Polymer Flooding for Heterogeneous Reservoir

Gels
Long-term polymer flooding exacerbates reservoir heterogeneity, intensifying intra- and inter-layer conflicts, which makes it difficult to recover the remaining oil. Therefore, further improvement in oil recovery after polymer flooding is essential.
Yunqian Long, Chenkan Zhang, Dandan Yin, Tao Huang, Hailong Zhang, Ming Yue, Xiaohe Huang   +6 more
doaj   +1 more source

DIFFERENTIATION OF CROATIAN BARLEY VARIETIES BY GRADIENT GEL SDS-PAGE AND ISOELECTRIC FOCUSING OF DRY GRAINS AND GREEN MALT HORDEINS [PDF]

Poljoprivreda, 2011
Applicability of polyacrylamide gel electrophoresis and isoelectric focusing of hordeins for discrimination of six two-rowed winter barley varieties (Angora, Sladoran, Rodnik, Rex, Martin and Barun) has been investigated.
Ivica Strelec, Elzabeta Has-Schön, Ljubinka Vitale   +2 more
doaj  

Polyacrylamide gels with selective recognition of the tetrameric molecular form of human growth hormone

eXPRESS Polymer Letters, 2017
Networks of polyacrylamide were studied for the possibility of imprinting of the oligomeric form of human growth hormone. The tetrameric molecular form of human growth hormone was molecularly imprinted for the first time.
R. Kublickas, C. Werner, B. Voit
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Urea Delays High-Temperature Crosslinking of Polyacrylamide for In Situ Preparation of an Organic/Inorganic Composite Gel

Gels
To address the rapid crosslinking reaction and short stability duration of polyacrylamide gel under high salinity and temperature conditions, this paper proposes utilizing urea to delay the nucleophilic substitution crosslinking reaction among ...
Li Liang, Junlong Li, Dongxiang Li, Jie Xu, Bin Zheng, Jikuan Zhao   +5 more
doaj   +1 more source

Synthesis and Mechanical Properties of Polyacrylamide Gel Doped with Graphene Oxide

Energies, 2022
Polyacrylamide (PAM)/polyethyleneimine (PEI) gels doped with graphene oxide (GO) were prepared. Their structure and properties were systematically studied by X-ray diffraction (XRD), Fourier transition infrared spectrum (FT-IR), Raman spectroscopy ...
Hai-Peng Zhang, Jing-Jing Cao, Wen-Bing Jiang, Yu-Qi Yang, Bo-Yuan Zhu, Xiao-Yu Liu, Yang Wu, Xin Sun, Ariane Felicite Bibiche Essouma Essouma, Jian Liu, Ting-Yan Xing   +10 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Electrophoretic analysis, labeling and isolation of Chlamydomonas reinhardtii flagellum membrane proteins

Acta Societatis Botanicorum Poloniae, 2015
SDS-polyacrylamide electrophoretic patterns of Chlamydomonas flagellum membrane proteins displayad 6 fractions, 3 PAS-positive among them. The surface radiolabeling of the flagellum membrane suggested an outer surface exposure of fraction '5', and ...
Aleksander F. Sikorski
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source