Results 201 to 210 of about 722,396 (378)

Anticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein

Advanced Science, EarlyView.
This study employed tRNASUAG, an anticodon‐engineered tRNA (ACE‐tRNA), to introduce a phosphorylatable serine into the C‐terminal domain of HBc by reading through its stop codon, thereby potentially promoting the ubiquitin‐proteasome degradation of HBc, and subsequently inhibiting HBV replication. Through a tRNASUAG‐gHBV1‐tRNASUAG‐gHBV2‐tRNASUAG tandem
Xingwen Yang, Huiying Sun, Ziheng Luo, Qinxin Zhang, Yarong Song, Jie Li, Xiaoyun Liu, Jie Wang   +7 more
wiley   +1 more source

[A protein-specific quantitative detection method based on polyacrylamide gel electrophoresis and online fluorescence imaging]. [PDF]

Se Pu
Zou R, Yu ZX, Guo ZH, Dai HZ, Zhang Q, Liu WW, Cao CX.   +6 more
europepmc   +1 more source

A modified clear-native polyacrylamide gel electrophoresis technique to investigate the oligomeric state of MBP-5-HT_3A-intracellular domain chimeras. [PDF]

Protein Expr Purif, 2019
Pandhare A, Stuebler AG, Pirayesh E, Jansen M.   +3 more
europepmc   +1 more source

Blue native polyacrylamide gel electrophoresis (BN-PAGE) for analysis of multiprotein complexes from cellular lysates.

Journal of Visualized Experiments, 2011
Gina J. Fiala, W. Schamel, B. Blumenthal
semanticscholar   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Purification of Native Dentilisin Complex from Treponema denticola by Preparative Continuous Polyacrylamide Gel Electrophoresis and Functional Analysis by Gelatin Zymography. [PDF]

Bio Protoc
Kamarajan P, Timm JC, Goetting-Minesky MP, Malone ET, Ganther S, Radaic A, Tafolla C, Fenno JC, Kapila YL.   +8 more
europepmc   +1 more source

Proteomic analysis of mucopolysaccharidosis I mouse brain with two-dimensional polyacrylamide gel electrophoresis. [PDF]

Mol Genet Metab, 2017
Ou L, Przybilla MJ, Whitley CB.
europepmc   +1 more source

An Evaluation of a Simple Polyacrylamide Gel Electrophoresis System for Lipoproteins and its Use for the Characterisation of Hyperlipoproteinaemia [PDF]

, 1979
Ying Foo, T.R. Tickner, D. G. Cramp
openalex   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Detection of Connexins in Liver Cells Using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis and Immunoblot Analysis. [PDF]

Methods Mol Biol, 2016
Willebrords J, Maes M, Yanguas SC, Cogliati B, Vinken M.   +4 more
europepmc   +1 more source