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Nanohydroxyapatite Incorporated Electrospun Polycaprolactone/Polycaprolactone–Polyethyleneglycol–Polycaprolactone Blend Scaffold for Bone Tissue Engineering Applications

Journal of Biomedical Nanotechnology, 2013
The present work is a comparative evaluation of physical and biological properties of electrospun biodegradable fibrous scaffolds based on polycaprolactone (PCL) and its blend with polycaprolactone-polyethyleneglycol-polycaprolactone (CEC) with and without nanohydroxyapatite (nHAP) particles.
Annie John
exaly   +4 more sources

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Synthesis of polycaprolactone: a review

Chemical Society Reviews, 2009
Polycaprolactone (PCL) is an important polymer due to its mechanical properties, miscibility with a large range of other polymers and biodegradability. Two main pathways to produce polycaprolactone have been described in the literature: the polycondensation of a hydroxycarboxylic acid: 6-hydroxyhexanoic acid, and the ring-opening polymerisation (ROP ...
Marianne, Labet, Wim, Thielemans
openaire   +2 more sources

Processing of Polycaprolactone and Polycaprolactone-Based Copolymers into 3D Scaffolds, and Their Cellular Responses

Tissue Engineering Part A, 2009
Synthetic polymers have attracted much attention in tissue engineering due to their ability to modulate biomechanical properties. This study investigated the feasibility of processing poly(epsilon-caprolactone) (PCL) homopolymer, PCL-poly(ethylene glycol) (PEG) diblock, and PCL-PEG-PCL triblock copolymers into three-dimensional porous scaffolds ...
Md Enamul, Hoque, Wong Yoke, San, Feng, Wei, Suming, Li, Ming-Hsi, Huang, Michel, Vert, Dietmar W, Hutmacher   +6 more
openaire   +4 more sources

Hydroxyapatite scaffolds infiltrated with thermally crosslinked polycaprolactone fumarate and polycaprolactone itaconate

Journal of Biomedical Materials Research Part A, 2011
AbstractIn this work, two unsaturated derivatives of polycaprolactone (PCL), polycaprolactone fumarate (PCLF), and polycaprolactone itaconate (PCLI), have been synthesized and used as an infiltrating polymer to improve the mechanical properties of brittle hydroxyapatite (HA) scaffolds.
Sharifi, Shahriar, Shafieyan, Yousef, Mirzadeh, Hamid, Bagheri-Khoulenjani, Shadab, Rabiee, Sayed Mahmood, Imani, Mohammad, Atai, Mohammad, Shokrgozar, Mohammad Ali, Hatampoor, Ali   +8 more
openaire   +2 more sources

Synthesis and characterization of lactose grafted polycaprolactone‐polysiloxane‐polycaprolactone copolymers

Polymer International, 2018
AbstractTo create new biofunctional materials, a polycaprolactone‐polysiloxane‐polycaprolactone (PCL‐PMVS‐PCL) carrying lactose was developed by ring‐opening polymerization and esterification reaction. 1H NMR and Fourier transform IR spectroscopy confirmed synthesis of the product.
Yajun Ren, Lei Wang, Xinxiang Cui, Libing Han, Qifeng Zhou, Xiaofeng Song   +5 more
openaire   +1 more source

Polycaprolactone for the Face

2020
The product is a sterile, totally bioresorbable implant, whose principle components are polycaprolactone (PCL) microspheres suspended in a gel carrier of carboxymethyl cellulose. Microspheres have a size range of 25–50 μm, and it should be injected with a 27G needle or a 27G or 25G cannula.
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Morphology and properties of polycaprolactone‐poly(dimethyl siloxane)‐polycaprolactone triblock copolymers

Journal of Polymer Science Part B: Polymer Physics, 1993
AbstractThe molecular structure, crystallization, solid‐state morphology, thermal properties, and phase behavior of two copolymers consisting of a poly(dimethylsiloxane) (PDMS) mid‐block coupled to polycaprolactone (PCL) end‐blocks were investigated.
Andrew J. Lovinger, B. J. Han, Frank J. Padden, Peter A. Mirau   +3 more
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DTA identification of polycaprolactone

Journal of Thermal Analysis, 1991
Polycaprolactone (PCL) is a new material used in orthopedics. It is characterized by an endothermic melting peak at about 61‡C, an endothermic decomposition peak at about 380‡C and an exothermic peak at about 453‡C. These three observed phenomena and the corresponding thermodynamic data made it easily possible to identify PCL among the other polymers ...
J. Kaloustian, A. M. Pauli, J. Pastor
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Polycaprolactone microparticles and their biodegradation

Polymer Degradation and Stability, 2000
Abstract Polycaprolactone (PCL) microparticles were prepared by an emulsification-solvent evaporation technique using various stabilizers such as gelatin, hydrophobically modified polyacrylamide derivative (PAM) and poly(vinyl alcohol) (PVA). It was shown that the particle size distribution of PCL microparticles was 13.4±4.7 (μm) in diameter with ...
D.R Chen, J.Z Bei, S.G Wang
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The influences of polycaprolactone-grafted nanoparticles on the properties of polycaprolactone composites with enhanced osteoconductivity

Composites Science and Technology, 2013
Abstract Bioceramic or inorganic nanoparticles made of SiO2, TiO2, SrO, and hydroxyapatite (HAP) have been reported to improve cell adhesion onto polymers. However, direct mixing of these nanoparticles with polymers often leads to their aggregation within the polymer matrix and subsequent deterioration of the material’s mechanical strength.
Ding-Wei Hong, Zhi-Teng Lai, Tsai-Sheng Fu, Tsung-Ting Tsai, I-Ming Chu, Po-Liang Lai   +5 more
openaire   +1 more source