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SAPHO syndrome complicated with relapsing polychondritis: A case report

International Journal of Rheumatic Diseases, 2023
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disease. The main clinical manifestation of SAPHO syndrome is an osteoarthropathy with cutaneous involvement.
Fengjiao Cao   +6 more
semanticscholar   +1 more source

Relapsing Polychondritis

Annals of Otology, Rhinology & Laryngology, 1989
Inflammatory destruction of cartilages, presumably on an autoimmune basis, characterizes relapsing polychondritis, a disease of varying severity and outcome. The otolaryngologist–head and neck surgeon is often the first physician contact, because the preponderance of signs and symptoms are in the head and neck, ie, auricular and nasal chondritis ...
J G, Batsakis, J T, Manning
openaire   +4 more sources

Pathogenic UBA1 variants associated with VEXAS syndrome in Japanese patients with relapsing polychondritis

Annals of the Rheumatic Diseases, 2021
Objectives To determine clinical and genetic features of individuals with relapsing polychondritis (RP) likely caused by pathogenic somatic variants in ubiquitin-like modifier activating enzyme 1 (UBA1).
N. Tsuchida   +12 more
semanticscholar   +1 more source

Relapsing Polychondritis

Zeitschrift für Rheumatologie, 2023
Relapsing polychondritis (RP) is a rare multisystemic disease predominantly involving the extracellular matrix. Typical manifestations are chondritis of the ears, nose and trachea as well as an asymmetrical oligoarthritis or polyarthritis of small and also larger joints. Various other involvements have also been described.
Benjamin, Makus, Thomas, Rose
openaire   +4 more sources

Tocilizumab in VEXAS relapsing polychondritis: a single-center pilot study in Japan

Annals of the Rheumatic Diseases, 2021
Recently, a rare severe autoinflammatory disease vacuoles, E1 enzyme, Xlinked, autoinflammatory, somatic (VEXAS) syndrome caused by somatic variants in the UBA1 gene was discovered. We reported the clinical features of eight relapsing polychondritis (RP)
Y. Kirino   +6 more
semanticscholar   +1 more source

Biologic therapy in relapsing polychondritis: navigating between options

Expert Opinion on Biological Therapy, 2022
Introduction Relapsing polychondritis (RP) is a rare systemic inflammatory disease of unknown etiology, primarily affecting cartilaginous tissue and proteoglycan-rich structures. Clinical manifestations vary from mild symptoms to occasional organ or life-
R. Padoan   +4 more
semanticscholar   +1 more source

Relapsing polychondritis

Clinics in Dermatology, 2006
Relapsing polychondritis is a rare disease most commonly presenting as inflammation of the cartilage of the ears and nose. Auricular chondritis, with red ears resembling infectious cellulitis, is the most common initial finding. Antibodies to type II collagen in cartilage are found, and the earlobes are classically spared. Chronic disease may result in
Ronald P, Rapini, Noranna B, Warner
openaire   +4 more sources

Clinical analysis of relapsing polychondritis with airway involvement

Journal of Laryngology and Otology, 2022
Objective To identify the clinical characteristics, treatment, and prognosis of relapsing polychondritis patients with airway involvement. Methods Twenty-eight patients with relapsing polychondritis, hospitalised in the First Hospital of Shanxi Medical ...
Songyu Zhai   +6 more
semanticscholar   +1 more source

Relapsing Polychondritis

Rheumatic Disease Clinics of North America, 2013
Relapsing polychondritis (RP) is a rare systemic autoimmune disease characterized by episodic, progressive inflammatory destruction of cartilage. It can occur as an overlap syndrome in patients with other rheumatologic conditions. The disease usually follows an indolent relapsing-remitting course, but occasionally it can progress rapidly and even cause
Chopra, Ratnesh   +2 more
openaire   +3 more sources

Relapsing Polychondritis

Optometry and Vision Science, 2000
Relapsing polychondritis (RPC) is a rare, chronic, and potentially fatal multisystemic inflammatory disorder targeting cartilaginous structures. This disorder is frequently associated with rheumatoid arthritis, systemic vasculitis, connective tissue diseases, and/or hematologic disorders.
M T, Chow, S F, Anderson
openaire   +4 more sources

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