Results 171 to 180 of about 73,510 (193)
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Comprehensive Physiology, 2017
ABSTRACTRenal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling.
Joseph, Ghata, Benjamin D, Cowley
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ABSTRACTRenal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling.
Joseph, Ghata, Benjamin D, Cowley
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New England Journal of Medicine, 2004
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
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Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
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1996
Abstract The term ‘Polycystic liver disease’ (PLO) is often used to describe a condition with numerous cysts scattered throughout the liver parenchyma (Poinso et al. 1954; Melnick 1955; Peltokallio 1970; Sanfelippo et al. 1974; Vauthey et al. 1991).
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Abstract The term ‘Polycystic liver disease’ (PLO) is often used to describe a condition with numerous cysts scattered throughout the liver parenchyma (Poinso et al. 1954; Melnick 1955; Peltokallio 1970; Sanfelippo et al. 1974; Vauthey et al. 1991).
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Reversing polycystic kidney disease
Nature Genetics, 2021A new study shows that re-expressing PKD genes early in the course of the disease can fully reverse polycystic kidney disease in mice. These results reveal an unexpected ability of the kidney to regenerate following genetic rescue of polycystin function.
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BJOG: An International Journal of Obstetrics & Gynaecology, 1976
SummarySex hormone binding globulin (SHBG) capacity was reduced in 9 of 31 patients with polycystic ovarian (PCO) disease and the mean level in PCO patients was significantly less (p<0·001) than normal. Serum testosterone levels were elevated in 21 of 32 PCO patients and the mean level was significantly elevated (p<0·001).
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SummarySex hormone binding globulin (SHBG) capacity was reduced in 9 of 31 patients with polycystic ovarian (PCO) disease and the mean level in PCO patients was significantly less (p<0·001) than normal. Serum testosterone levels were elevated in 21 of 32 PCO patients and the mean level was significantly elevated (p<0·001).
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Neonatal Polycystic Kidney Disease
Clinics in Perinatology, 2014This article provides an up-to-date comprehensive review and summary on neonatal polycystic kidney disease (PKD) with emphasis on the differential diagnosis, clinical manifestations, diagnostic techniques, and potential therapeutic approaches for the major causes of neonatal PKD, namely hereditary disease, including autosomal recessive and autosomal ...
Priya, Verghese, Yosuke, Miyashita
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Calcification in Polycystic Disease
Radiology, 1977Two patients with polycystic disease demonstrated extensive calcification in the kidneys, liver, and spleen. Though flecks of calcium have been noted in the walls of such cysts, to the authors' knowledge, curvillinear, arcuate, and central amorphous calcifications have not been previously reported.
R, Kutcher, M, Schneider, D H, Gordon
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Familial Polycystic Ovarian Disease
Endocrinology and Metabolism Clinics of North America, 1988Emphasis is placed on the heterogeneity of the phenotypic presentation of PCOD. It is the common expression of an unknown number of disorders and thus is a sign and not a specific diagnosis. Two essential features are arrested follicular maturation and atresia of follicles.
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