Results 11 to 20 of about 73,510 (193)
Polycystic Kidney Disease [PDF]
Annual Review of Medicine, 2009 A number of inherited disorders result in renal cyst development. The most common form, autosomal dominant polycystic kidney disease (ADPKD), is a disorder most often diagnosed in adults and caused by mutation in PKD1 or PKD2. The PKD1 protein, polycystin-1, is a large receptor-like protein, whereas polycystin-2 is a transient receptor potential ...
Peter C, Harris, Vicente E, Torres
+7 more sources
Polycystic Kidney Disease [PDF]
Journal of the American Society of Nephrology, 2007 Renal cysts are common clinical findings, often incidentally discovered in the course of evaluating other problems. They may be either acquired or seen in association with a number of inherited and congenital disorders. The most common disorder, autosomal dominant polycystic kidney disease (ADPKD), is an important cause of end-stage renal disease (ESRD)
Peter, Igarashi, Stefan, Somlo
openaire +2 more sources
Polycystic liver disease [PDF]
BMJ Case Reports, 2014 A widespread use of ultrasound (US) examination is contributing to an increase in the diagnosis of renal and hepatic cysts. However, the vast majority of these lesions are benign with an indolent course during the patient's lifespan. Adult polycystic kidney disease (APKD) is one of the most common diagnosed entities.
Rodrigo Nazário, Leão +2 more
openaire +2 more sources
Polycystic liver disease [PDF]
Revista Española de Enfermedades Digestivas, 2009 A 54-year-old man had an asymptomatic elevation of cytolysis-related enzymes, GGT, and alkaline phosphatase, detected at a routine laboratory study. The patient reported no alcohol abuse, no history of liver disease, and no constitutional syndrome. Physical examination showed a good general status, normal colored skin and mucosas, and no stigmata of ...
Albandea Moreno,C. +5 more
openaire +3 more sources
Polycystic kidney disease [PDF]
Nature Reviews Disease Primers, 2018 Cystic kidneys are common causes of end-stage renal disease, both in children and in adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are cilia-related disorders and the two main forms of monogenic cystic kidney diseases.
Bergmann, C. +5 more
openaire +6 more sources
Polycystic kidney disease complicates renal pathology in a family with Fabry disease
Molecular Genetics and Metabolism Reports, 2022 Fabry disease is a rare lysosomal storage disorder that primarily affects the heart and kidneys, often presenting with reduced renal function. Polycystic kidney disease is a renal condition in which cysts are found, which have a different presentation ...
Leepakshi Johar +7 more
doaj +1 more source
Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]
, 2018 Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre +10 more
core +2 more sources
Bulletin de la Dialyse à Domicile, 2023 Summary Autosomal dominant polycystic hepatorenal disease is a common chronic kidney disease. Among the proposed replacement therapies, peritoneal dialysis (PD) concerns less than 7% of polycystic patients. The underutilization of PD is due to the fear
Fatouma Toure
doaj +1 more source
Impaired carotid viscoelastic properties in women with polycystic ovaries [PDF]
, 2002 Background-The purpose of this study was to assess the elastic properties of the carotid arteries in women with polycystic ovarian syndrome, asymptomatic women with polycystic ovaries.
Hardiman, P, Lakhani, K, Seifalian, AM
core +1 more source
Polycystic Kidney Disease [PDF]
The Journal of Clinical Hypertension, 2005 Polycystic kidney disease, an inherited systemic disorder, is characterized by the development of multiple cysts in the kidneys and other organs. Patients can present at any age, but more often come to clinical attention (unless there is a family history) after age 30. Patients who are diagnosed before age 30 have a worse renal survival.
Pamela J, Fall, L Michael, Prisant
openaire +2 more sources