Results 61 to 70 of about 9,152,470 (385)

Polycystic liver disease presenting with an exudative pleural effusion: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Polycystic liver disease is asymptomatic in 95% of patients. In the remaining 5% it causes symptoms due to the local mass effect of the polycystic liver. We describe the case of a patient who presented with symptoms of a pleural effusion and
Woolnough Kerry   +2 more
doaj   +1 more source

Genetics of Autosomal Recessive Polycystic Kidney Disease and Its Differential Diagnoses

open access: yesFrontiers in Pediatrics, 2018
Autosomal recessive polycystic kidney disease (ARPKD) is a hepatorenal fibrocystic disorder that is characterized by enlarged kidneys with progressive loss of renal function and biliary duct dilatation and congenital hepatic fibrosis that leads to portal
C. Bergmann
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

PCONet: A Convolutional Neural Network Architecture to Detect Polycystic Ovary Syndrome (PCOS) from Ovarian Ultrasound Images [PDF]

open access: yesarXiv, 2022
Polycystic Ovary Syndrome (PCOS) is an endrocrinological dysfunction prevalent among women of reproductive age. PCOS is a combination of syndromes caused by an excess of androgens - a group of sex hormones - in women. Syndromes including acne, alopecia, hirsutism, hyperandrogenaemia, oligo-ovulation, etc. are caused by PCOS. It is also a major cause of
arxiv  

Polycystic liver disease with lethal abdominal wall rupture: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Polycystic liver disease is a clinical feature of autosomal dominant polycystic kidney disease, and it can sometimes cause health damage more serious than polycystic kidney.
Daichi Akuzawa   +7 more
doaj   +1 more source

Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.

open access: yesJournal of Clinical Investigation, 2015
The HSP40 cochaperone SEC63 is associated with the SEC61 translocon complex in the ER. Mutations in the gene encoding SEC63 cause polycystic liver disease in humans; however, it is not clear how altered SEC63 influences disease manifestations.
S. Fedeles   +7 more
semanticscholar   +1 more source

Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism [PDF]

open access: yes, 2016
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis.
Abruzzese, Giselle Adriana   +6 more
core   +2 more sources

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

Deep Linear Discriminant Analysis with Variation for Polycystic Ovary Syndrome Classification [PDF]

open access: yesarXiv, 2023
The polycystic ovary syndrome diagnosis is a problem that can be leveraged using prognostication based learning procedures. Many implementations of PCOS can be seen with Machine Learning but the algorithms have certain limitations in utilizing the processing power graphical processing units.
arxiv  

Autosomal dominant polycystic kidney disease with diffuse proliferative glomerulonephritis - an unusual association: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2010
Introduction Autosomal dominant polycystic kidney disease is an inherited disorder that is characterized by the development and growth of cysts in the kidneys and other organs.
Kapoor Vinay   +6 more
doaj   +1 more source

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