Results 81 to 90 of about 9,152,470 (385)

Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases. [PDF]

open access: yesPLoS ONE, 2015
Biliary cysts in adult patients affected by polycystic liver disease are lined by cholangiocytes that proliferate, suggesting that initiation of cyst formation depends on proliferation.
Jean-Bernard Beaudry   +5 more
doaj   +1 more source

Recent Advances in the Management of Autosomal Dominant Polycystic Kidney Disease.

open access: yesAmerican Society of Nephrology. Clinical Journal, 2018
Autosomal dominant polycystic kidney disease (ADPKD), the most common monogenic cause of ESKD, is characterized by relentless development of kidney cysts, hypertension, and destruction of the kidney parenchyma. Over the past few years, major advancements
F. Chebib, V. Torres
semanticscholar   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

open access: yes, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia   +4 more
core   +2 more sources

A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions

open access: yesAdvanced Science, EarlyView.
An open‐source, low‐cost 3D perfusion system integrating bioprinted scaffolds and live‐imaging overcomes 2D culture limitations. Modeling the cerebrospinal fluid‐filled subarachnoid space, it reveals flow‐dependent focal adhesion kinase activation in meningothelial cells, demonstrating a powerful platform for studying mechanobiology and creating ...
Subashree Srinivasan   +7 more
wiley   +1 more source

Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome

open access: yesCardiovascular Diabetology, 2018
BackgroundPolycystic ovary syndrome (PCOS) is associated with obesity and low grade inflammation and the risk for cardiovascular disease (CVD) could be increased in PCOS.MethodsNational register-based study including women with PCOS and no previous ...
D. Glintborg   +4 more
semanticscholar   +1 more source

The effect of atorvastatin on pancreatic beta cell requirement in women with polycystic ovary syndrome [PDF]

open access: yes, 2017
Background There is an increased risk of developing T2DM in women with polycystic ovary syndrome (PCOS) and there is evidence that statins improve metabolic parameters in these patients.
Atkin, Stephen L.   +3 more
core   +2 more sources

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

open access: yesAdvanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang   +11 more
wiley   +1 more source

Epistasis Detection Via the Joint Cumulant [PDF]

open access: yesarXiv, 2021
Selecting influential nonlinear interactive features from ultrahigh dimensional data has been an important task in various fields. However, statistical accuracy and computational feasibility are the two biggest concerns when more than half a million features are collected in practice.
arxiv  

Characteristics of polycystic ovary syndrome throughout life

open access: yesTherapeutic Advances in Reproductive Health, 2020
Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age. It is a complex disease in which genetic, endocrine, environmental, and behavioral factors are intertwined, giving rise to a heterogeneous phenotype with ...
Yvonne V. Louwers, Joop S.E. Laven
doaj   +1 more source

Sexual and relational satisfaction in couples where the woman has polycystic ovary syndrome: a dyadic analysis [PDF]

open access: yes, 2014
STUDY QUESTION: How are objective characteristics of polycystic ovary syndrome (PCOS) and PCOS-related concerns associated with the sexual and relational satisfaction of PCOS women and their partners? SUMMARY ANSWER: Both objective PCOS characteristics (
Buysse, Ann   +5 more
core   +2 more sources

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