Results 121 to 130 of about 43,386 (236)

Aldosterone as a renal growth factor [PDF]

open access: yes, 2010
Aldosterone regulates blood pressure through its effects on the cardiovascular system and kidney. Aldosterone can also contribute to the development of hypertension that leads to chronic pathologies such as nephropathy and renal fibrosis.
Dooley, Ruth   +2 more
core   +1 more source

Genetic linkage study of family members of a patient with adult polycystic kidney disease [PDF]

open access: yes, 1999
OBJECTIVE. To study the feasibility of making an early diagnosis of adult polycystic kidney disease by using genetic linkage analysis in Hong Kong. DESIGN. Genetic linkage study. SETTING. University teaching hospital, Hong Kong. PARTICIPANTS.
Chan, DTM   +4 more
core  

A Case of Renal Transcatheter Arterial Embolization with Ethanol in Autosomal Dominant Polycystic Kidney Disease for Volume Reduction [PDF]

open access: yes, 2011
We report herein the case of a 76-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) and chronic renal failure resulting in intractable abdominal distension and anorexia.
Gobara, Hideo   +5 more
core   +1 more source

Autosomal dominant polycystic kidney disease in children

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2016
Autosomal dominant polycystic kidney disease (ADPKD) presenting in adults is well documented, but the presentation in children is uncommon and is unclear why the disease presents early.
Kiran Chandra Patro   +2 more
doaj  

Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease [PDF]

open access: yes, 2014
BACKGROUND: Neks, mammalian orthologs of the fungal protein kinase never-in-mitosis A, have been implicated in the pathogenesis of polycystic kidney disease. Among them, Nek1 is the primary protein inactivated in kat2J mouse models of PKD.
Charity Juang   +5 more
core   +3 more sources

[Autosomal dominant polycystic kidney].

open access: yesRevista do Hospital das Clinicas, 1996
A 48-year-old male had autosomic dominant polycystic kidneys with dimensions, to the best of our knowledge, never previously reported; the right kidney weighed 15,100 g and measured 53 x 33 x 9cm and the left one 10.200 g and 46 x 21 x 7cm, with cysts measuring up to 14cm in diameter.
S, Jorge Adad   +4 more
openaire   +1 more source

Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney Disease: The DIPAK 1 Randomized Clinical Trial

open access: yesJournal of the American Medical Association (JAMA), 2018
Importance Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst formation in both kidneys and loss of renal function, eventually leading to a need for kidney replacement therapy.
E. Meijer   +22 more
semanticscholar   +1 more source

Renal Transplantation in Autosomal Dominant Polycystic Kidney Disease [PDF]

open access: yesEuropean Medical Journal Nephrology, 2015
Autosomal dominant polycystic kidney disease (ADPKD) affects approximately 1 in 1,000 people in the general population. The natural history of ADPKD includes the progression of chronic kidney disease to end-stage renal disease (ESRD) in a large ...
Andrzej Kulesza   +2 more
doaj  

New rat model that phenotypically resembles autosomal recessive polycystic kidney disease [PDF]

open access: yes, 2000
Numerous murine models of polycystic kidney disease (PKD) have been described. While mouse models are particularly well suited for investigating the molecular pathogenesis of PKD, rats are well established as an experimental
Dokkum, R.P.E. (Richard) van   +8 more
core   +1 more source

Monoallelic IFT140 pathogenic variants are an important cause of the autosomal dominant polycystic kidney-spectrum phenotype.

open access: yesAmerican Journal of Human Genetics, 2021
Sarah R. Senum   +27 more
semanticscholar   +1 more source

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