Results 131 to 140 of about 43,386 (236)

Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease.

Journal of the American Society of Nephrology, 2018
BACKGROUND In patients with autosomal dominant polycystic kidney disease (ADPKD), most of whom have a mutation in PKD1 or PKD2, abnormally large numbers of macrophages accumulate around kidney cysts and promote their growth. Research by us and others has
M. Cassini, Vijayakumar R. Kakade, E. Kurtz, Parker Sulkowski, Peter Glazer, Richard Torres, S. Somlo, L. Cantley   +7 more
semanticscholar   +1 more source

Estudo de ligação molecular do rim policístico do adulto (ADPKD) com primers do cromossomo 16 (PKD1) e 4 (PKD2). [PDF]

, 1998
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Médica, Curso de Medicina, Florianópolis ...
Ferreira, Fernando Romariz
core  

Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease

Molecular and Cellular Biology, 2017
Autosomal dominant polycystic kidney disease (ADPKD) constitutes the most inherited kidney disease. Mutations in the PKD1 and PKD2 genes, encoding the polycystin 1 and polycystin 2 Ca2+ ion channels, respectively, result in tubular epithelial cell ...
Y. Ishimoto, R. Inagi, D. Yoshihara, M. Kugita, S. Nagao, A. Shimizu, Norihiko Takeda, Masaki Wake, K. Honda, Jing Zhou, M. Nangaku   +10 more
semanticscholar   +1 more source

Results of kidney transplantation in patients with end-stage renal failure caused by autosomal dominant polycystic kidney disease

Вестник трансплантологии и искусственных органов, 2019
Aim. To investigate the renal transplantation results for patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (PKD).Materials and methods.
V. S. Daineko, A. N. Ananiev, E. S. Nevirovich, A. E. Skvorcov, S. A. Budylev, А. N. Selivanov, M. M. Moskalenko, V. A. Manukovskiy, O. N. Reznik   +8 more
doaj   +1 more source

Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disorder that is caused by mutations in the genes PKD1 and PKD2 encoding polycystin-1 and polycystin-2, respectively.
Dengjel, Jörn, Diedrich, Britta
core  

CLINICAL CASE OF AUTOSOMAL DOMINANT POLYCYSTOSIS OF THE KIDNEY IN A CHILD WITH CONNECTIVE TISSUE DYPLASIA

Мать и дитя в Кузбассе, 2022
The relevance of the problem of autosomal dominant polycystic kidney disease in childhood is due to age-related features of the formation of renal cysts and clinical manifestations, the frequent development of arterial hypertension syndrome and ...
Андрей Васильевич Налетов, Любовь Феликсовна Чалая, Оксана Николаевна Москалюк, Мария Александровна Мацынина   +3 more
doaj  

Autophagy and Autosomal Dominant Polycystic Kidney Disease

Turkish Journal of Nephrology, 2023
Özgür Akın Oto, Charles L. Edelstein
doaj   +1 more source

Human medicines European public assessment report (EPAR): Jinarc, tolvaptan, Polycystic Kidney, Autosomal Dominant, Date of authorisation: 27/05/2015, Revision: 13, Status: Authorised

Case Medical Research, 2019

semanticscholar   +1 more source

Predictors of progression in autosomal dominant and autosomal recessive polycystic kidney disease

Pediatric nephrology (Berlin, West), 2021
Eric G. Benz, Erum A. Hartung
semanticscholar   +1 more source

Immune microenvironment in autosomal dominant polycystic kidney disease

Genes and Diseases
Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary renal disorder characterized by the progressive development of fluid-filled cysts within the kidneys, leading to renal dysfunction and potentially life-threatening complications.
Cheng Xue, Xinming Li, Chenchen Zhou, Changlin Mei, Zhiguo Mao   +4 more
doaj   +1 more source