Results 11 to 20 of about 25,511 (203)
Autosomal dominant polycystic kidney disease in children
Saudi Journal of Kidney Diseases and Transplantation, 2016 Autosomal dominant polycystic kidney disease (ADPKD) presenting in adults is well documented, but the presentation in children is uncommon and is unclear why the disease presents early.
Kiran Chandra Patro +2 more
doaj +7 more sources
Autosomal Dominant Polycystic Kidney Disease [PDF]
Advances in Chronic Kidney Disease, 2010 Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic form of kidney disease and affects 1 in 500 to 1,000 individuals worldwide, regardless of ethnicity. It is characterized by progressive renal cyst formation, which distorts normal kidney architecture and ultimately causes 5% of all cases of end-stage renal disease (ESRD) in
Terry Watnick, York Pei
+9 more sources
Autosomal dominant polycystic kidney disease [PDF]
Canadian Medical Association Journal, 2017 Mutations in PKD1 or PKD2 cause autosomal dominant polycystic kidney disease, which proceeds to kidney failure in 70% of patients between the fourth and seventh decade of life.[1][1] Signs of autosomal dominant polycystic kidney disease (i.e., numerous cysts and enlargement of the kidneys) may ...
Matthew B. Lanktree, Arlene B Chapman
openaire +4 more sources
Autosomal dominant polycystic kidney disease [PDF]
BMJ, 1994 When the BMJ last published an editorial on adult autosomal dominant polycystic kidney disease1 there was no chromosomal assignment for the disorder. Two have since been recognised. The first, designated PKD-1,2 has been localised to a narrow region of about half a million base pairs on the short arm of chromosome 16, but the specific gene has not yet ...
A K Saggar-Malik +2 more
openaire +3 more sources
Autosomal Dominant Polycystic Kidney Disease
Saudi Journal of Kidney Diseases and Transplantation, 1999 Schwenger Vedat, Zeier Martin
doaj +2 more sources
Autosomal dominant polycystic kidney disease [PDF]
Srpski arhiv za celokupno lekarstvo, 2008 Autosomal dominant polycystic kiney disease is a hereditary systemic disorder, characterized by the developement of cysts, mainly in the kidney and liver, also with gastrointestinal and cardiovascular abnormalities. It affects 4 to 6 million people wordwide and accounts for end-stage renal disease in 7-10% of dialysis patients.
openaire +4 more sources
Autosomal dominant polycystic kidney disease [PDF]
Clinical Medicine, 2009 Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disease with a prevalence of 1:400 to 1:1,000 live births.[1][1] It is the most common genetic cause of renal failure, accounting for 10% of patients on dialysis.
Chern Li Chow, Albert C.M. Ong
openaire +3 more sources
Autosomal dominant polycystic kidney disease. [PDF]
Journal of the American Society of Nephrology, 1993 Autosomal dominant polycystic kidney disease (ADPKD) is an important cause of medical morbidity in the United States that affects one-half million persons and accounts for ESRD in about 10% of the chronic dialysis population. In addition to its effects on the kidney, the disease has important manifestations in the cardiovascular system (aneurysms ...
F G Toback, J C Lieske
openaire +3 more sources
Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease [PDF]
, 2018 Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the development of kidney cysts leading to kidney failure in adulthood. Inhibition of mammalian target of rapamycin (mTOR) slows polycystic kidney disease (PKD) progression in ...
Arcaro, Alexandre +10 more
core +2 more sources
Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease [PDF]
, 2016 The neurohypophysial hormone arginine vasopressin (AVP) acts by three distinct receptor subtypes: V1a, V1b, and V2. In the liver, AVP is involved in ureogenesis, glycogenolysis, neoglucogenesis and regeneration. No data exist about the presence of AVP in
Alpini, Gianfranco +11 more
core +1 more source