Results 11 to 20 of about 4,269 (127)
Sociodemographic characteristics and clinical features of patients with adult polycystic kidney disease undergoing hemodialysis [PDF]
Aims: To analyze the socio-demographic and clinical characteristics of patients with adult polycystic kidney disease admitted to hemodialysis services in Northwestern Paraná state, Brazil.
Tsuneto, Luiza Tamie +13 more
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Autosomal dominant polycystic kidney disease [PDF]
When the BMJ last published an editorial on adult autosomal dominant polycystic kidney disease1 there was no chromosomal assignment for the disorder. Two have since been recognised. The first, designated PKD-1,2 has been localised to a narrow region of about half a million base pairs on the short arm of chromosome 16, but the specific gene has not yet ...
A K, Saggar-Malik +2 more
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Autosomal dominant polycystic kidney disease in Colombia
Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic cause of chronic kidney disease (CKD) that requires dialysis. Knowing geographical clusters can be critical for early diagnosis, progression control, and genetic counseling.
Jessica T. Camargo +6 more
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Hydronephrosis in autosomal dominant polycystic kidney disease [PDF]
An 18-year-old patient with autosomal dominant polycystic kidney disease (ADPKD) was enrolled in a clinical study testing a novel drug therapy to retard disease progression. He reported chronic intermittent right-sided flank pain that began 2 years earlier and was attributed to ADPKD at that time.
Kistler, A D +3 more
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Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. [PDF]
Identifying and characterising potential new therapeutic agents to target cell proliferation may provide improved treatments for neoplastic disorders such as cancer and polycystic ...
Baines, D +20 more
core +1 more source
Hypertension in Autosomal Dominant Polycystic Kidney Disease [PDF]
Hypertension is common and occurs in a majority of autosomal dominant polycystic kidney disease (ADPKD) patients before the loss of kidney function. Hypertension relates to progressive kidney enlargement and is a significant independent risk factor for progression to ESRD.
Arlene B, Chapman +2 more
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Autosomal Dominant Polycystic Kidney Disease
Over 50% of people affected with autosomal dominant polycystic kidney disease (ADPKD) will develop kidney failure, making ADPKD the 4th most common cause of end-stage kidney disease. ADPKD is a systemic condition affecting the kidneys, liver, heart, vasculature, and other organ systems.
Maria Lourdes Gonzalez Suarez +2 more
+7 more sources
Autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kiney disease is a hereditary systemic disorder, characterized by the developement of cysts, mainly in the kidney and liver, also with gastrointestinal and cardiovascular abnormalities. It affects 4 to 6 million people wordwide and accounts for end-stage renal disease in 7-10% of dialysis patients.
openaire +2 more sources
What Is Autosomal Dominant Polycystic Kidney Disease?
International audienceThis JAMA Patient Page describes autosomal dominant polycystic kidney disease, its signs and symptoms, diagnosis, and treatment ...
Alam, Ahsan +5 more
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Severe autosomal dominant polycystic kidney disease [PDF]
A 61-year-old man with a known history of autosomal dominant polycystic kidney disease (ADPKD) and stage IV chronic kidney disease presented with a 6-month history of abdominal pain, nausea, vomiting and fatigue. In addition to the ADPKD, the right kidney had a 4.4 cm inferior pole mass concerning for renal cell carcinoma (RCC).
Neal S Gerstein +2 more
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