Results 211 to 220 of about 43,386 (236)

Assessing Risk of Rapid Progression in Autosomal Dominant Polycystic Kidney Disease and Special Considerations for Disease-Modifying Therapy.

American Journal of Kidney Diseases, 2021
Autosomal Dominant Polycystic Kidney Disease is the most common inherited cause of kidney failure accounting for 5-10% of cases. Predicting which patient would progress rapidly to kidney failure is critical to assess the risk-benefit ratio of any ...
F. Chebib, V. Torres
semanticscholar   +1 more source

Autosomal Dominant Polycystic Kidney Disease

Primary Care: Clinics in Office Practice, 2020
Autosomal Dominant Polycystic Kidney Disease is an inherited multisystemic disorder of the renal tubules with subsequent formation of multiple cysts and enlargement of the kidney, affecting various organs. Diagnosis is initially suspected in those with family history and/or individuals who develop hypertension early on (secondary hypertension) or ...
Parvathi, Perumareddi, Darin P, Trelka
openaire   +3 more sources

Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease

NEJM Evidence, 2021
Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease The effect of increased water intake on kidney cyst growth in patients with polycystic kidney disease was compared for two groups randomly assigned to either prescribed or ad libitum
Gopi K Rangan, Annette Wong, A. Munt, Jennifer Zhang, S. Saravanabavan, Margaret Allman-Farinelli, S. Badve, Neil Boudville, Bradley J. Erickson, Mangalee R. Fernando, Sheryl L. Foster, Adriana Gregory, I. Haloob, Carmel M. Hawley, David W. Johnson, Timothy L. Kline, Vincent W. Lee, Maureen A. Lonergan, Elaine Pascoe, A. Rangan, Simon D Roger, Kamal Sud, Vicente E. Torres, Sundareswari V. Adinarayanan, D. Harris   +24 more
semanticscholar   +1 more source

Autosomal Dominant Polycystic Kidney Disease

Advances in Kidney Disease and Health
Over 50% of people affected with autosomal dominant polycystic kidney disease (ADPKD) will develop kidney failure, making ADPKD the 4th most common cause of end-stage kidney disease. ADPKD is a systemic condition affecting the kidneys, liver, heart, vasculature, and other organ systems.
Maria Lourdes Gonzalez Suarez, Silvia Titan, Neera K. Dahl   +2 more
  +6 more sources

Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease

Science Translational Medicine, 2020
Pharmacological induction of NRF2 restores redox homeostasis and slows cystogenesis in mouse models of polycystic kidney disease. Antioxidants dominate ADPKD Autosomal dominant polycystic kidney disease (ADPKD) is a relatively common genetic disorder ...
Yi Lu, Yongzhan Sun, Zhiheng Liu, Yumei Lu, Xu Zhu, Bingxue Lan, Zeyun Mi, Lin Dang, Na Li, Wen-hu Zhan, Lu Tan, J. Pi, H. Xiong, Lirong Zhang, Yupeng Chen   +14 more
semanticscholar   +1 more source

Autosomal dominant polycystic kidney disease

The Lancet, 2007
Autosomal dominant polycystic kidney disease is the most prevalent, potentially lethal, monogenic disorder. It is associated with large interfamilial and intrafamilial variability, which can be explained to a large extent by its genetic heterogeneity and modifier genes.
Vicente E, Torres, Peter C, Harris, Yves, Pirson   +2 more
openaire   +2 more sources

Autosomal Dominant Polycystic Kidney Disease

New England Journal of Medicine, 1990
Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease occurring in 1 in 200 to 1 in 1,000 individuals. ADPKD is characterized by cystic lesions in the kidneys and often by structural abnormalities in the gastrointestinal tract and cardiovascular system.
openaire   +3 more sources

Autosomal dominant polycystic kidney disease

2018
Based on an estimated population prevalence of between 1 in 400 and 1 in 1000, there are over 60,000 individuals with or at risk of developing complications associated with autosomal dominant polycystic kidney disease (ADPKD) in the United Kingdom. This equates to over 300,000 people in the United States and 7 million worldwide.
Albert C. M. Ong, Richard Sandford
openaire   +2 more sources