Results 91 to 100 of about 4,765 (160)

Diagnostic value of fetal MRI in evaluating fetal urinary anomalies

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Purpose: To detect the accuracy of fetal MRI in diagnosing urinary tract anomalies in comparison with ultrasonographic findings and fetal outcome. Methods: We examined 30 fetuses with sonographically suspected congenital urinary tract anomalies by 2D/3D ...
Noha Hosam El Din Behairy, Lamiaa Adel Salah El Din, Naglaa Mohamed Fahmy Hanoun, Maged Abd El Raof, Mohamed Abd El Kader Ali   +4 more
doaj   +1 more source

MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease [PDF]

, 2008
Hyperproliferation of bile duct epithelial cells due to cell-cycle dysregulation is a key feature of cystogenesis in polycystic liver diseases (PCLDs). Recent evidence suggests a regulatory role for microRNAs (miRNAs) in a variety of biological processes,
Banales, J.M. (Jesús M.), LaRusso, N.F. (Nicholas F.), Lee, S.O. (Seung-Ok), Masyuk, A.I. (Anatoly I.), Masyuk, T.V. (Tatyana V.), Splinter, P.L. (Patrick L.), Stroope, A. (Angela)   +6 more
core  

Nephronophthisis: a genetically diverse ciliopathy. [PDF]

, 2011
Nephronophthisis (NPHP) is an autosomal recessive cystic kidney disease and a leading genetic cause of established renal failure (ERF) in children and young adults.
Eley, L., Hynes, A.M., Sayer, J.A., Simms, R.J.   +3 more
core   +4 more sources

The Excess of Carriers in Rare Disorders Suggests a Nonpathogenic Effect for Most Variants of Uncertain Significance

Clinical Genetics, Volume 107, Issue 3, Page 323-327, March 2025.
We compared the reported prevalence of rare recessive diseases obtained from epidemiological data with the population mutational load in their causative genes. If the knowledge of the genetic etiology of the disease is correct, the two estimates should be similar (A).
Stefano Medaglia, Jaume Reig‐Palou, Ariadna Bellés, Nerea Moreno‐Ruiz, Jairo Rodríguez, Xavier Armengol, Juan Ignacio Aróstegui, Lluís Armengol, Juan José Guillén, Hafid Laayouni, Ferran Casals   +10 more
wiley   +1 more source

Polycystic kidney disease: inheritance, pathophysiology, prognosis, and treatment

International Journal of Nephrology and Renovascular Disease, 2010
Christian R Halvorson1, Matthew S Bremmer1, Stephen C Jacobs11Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USAAbstract: Both autosomal dominant and recessive polycystic kidney disease are conditions with severe ...
Christian R Halvorson, Matthew S Bremmer, Stephen C Jacobs   +2 more
doaj  

Inhibition of cyst growth in PCK and Wpk rat models of polycystic kidney disease with low doses of peroxisome proliferator-activated receptor γ agonists [PDF]

, 2016
Background and Objectives The studies were designed to test the efficacy of two peroxisome proliferator-activated receptor γ (PPARγ) agonists in two rodent models of polycystic kidney disease (PKD).
Blazer-Yost, Bonnie L., Flaig, Stephanie M., Gattone, Vincent H.   +2 more
core   +1 more source

Adult Renal Cysts: When to Intervene?

Trends in Urology &Men's Health, Volume 16, Issue 1, February 2025.
ABSTRACT Renal cysts are common in the adult population and can be challenging to decide which need intervention or follow‐up. Assessment based on history, examination and cross‐sectional imaging will determine the disposition for patients based on their risk of malignancy and symptoms. The Bosniak Classification is used to stratify risk of malignancy,
Madeleine Bain, Adib Rahman, Nicholas Rukin, Devang Desai   +3 more
wiley   +1 more source

Autosomal recessive polycystic kidney disease [PDF]

American Journal of Obstetrics and Gynecology, 2021
openaire   +2 more sources

Prenatal MR imaging features of Caroli syndrome in association with autosomal recessive polycystic kidney disease

Radiology Case Reports, 2019
Caroli syndrome, which is characterized by saccular and fusiform dilatation of the biliary ducts, is usually observed in association with autosomal recessive polycystic kidney disease (ARPKD).
Amanda Rivas, Monica Epelman, MD, Enrico Danzer, MD, N. Scott Adzick, MD, Teresa Victoria, MD, PhD   +4 more
doaj  

Clinical and genetic characteristics of autosomal recessive polycystic kidney disease in Oman

BMC Nephrology, 2020
Background There is a high prevalence of rare genetic disorders in the Middle East, and their study provides unique clinical and genetic insights. Autosomal recessive polycystic kidney disease (ARPKD) is one of the leading causes of kidney and liver ...
Intisar Al Alawi, Elisa Molinari, Issa Al Salmi, Fatma Al Rahbi, Adhra Al Mawali, John A. Sayer   +5 more
doaj   +1 more source