Results 91 to 100 of about 1,110,820 (300)

The PROPKD Score: A New Algorithm to Predict Renal Survival in Autosomal Dominant Polycystic Kidney Disease.

Journal of the American Society of Nephrology, 2016
The course of autosomal dominant polycystic kidney disease (ADPKD) varies among individuals, with some reaching ESRD before 40 years of age and others never requiring RRT.
E. Cornec-Le Gall, M. Audrézet, A. Rousseau, M. Hourmant, É. Renaudineau, C. Charasse, M. Morin, M. Moal, J. Dantal, B. Wehbe, R. Perrichot, T. Frouget, C. Vigneau, J. Potier, P. Jousset, M. Guillodo, P. Siohan, N. Terki, T. Sawadogo, D. Legrand, V. Menoyo-Calonge, S. Benarbia, D. Besnier, H. Longuet, C. Férec, Y. Le Meur   +25 more
semanticscholar   +1 more source

MicroRNAs and Polycystic Kidney Disease [PDF]

Drug Discovery Today: Disease Models, 2013
Polycystic kidney disease (PKD), the most common genetic cause of chronic renal failure, is characterized by the presence of numerous fluid-filled cysts in renal parenchyma. Despite recent progress, no FDA-approved therapy is available to retard cyst growth.
Ronak Lakhia, Vishal Patel, Sachin Hajarnis   +2 more
openaire   +4 more sources

Interrupted Aortic Arch in an Adult with Polycystic Kidney Disease

Case Reports in Medicine, 2013
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and is responsible for 8–10% of patients with end-stage renal failure.
Ayşe Şeker Koçkara, Mansur Kayataş, Can Huzmeli, Ferhan Candan, Cesur Gümüş   +4 more
doaj   +1 more source

Combined liver-kidney transplantation and the effect of preformed lymphocytotoxic antibodies [PDF]

, 1994
Thirty-eight sequentially placed liver and kidney allografts were evaluated with respect to patient and graft survival, and the influence of preformed lymphocytotoxic antibodies was analysed.
A.Jake Demetris, Calne, Demetris, Duquesnoy, Eid, Ellis, Flye, Fung, Fung, Furuya, George Mazariegos, Gonwa, Gordon, Gordon, Gugenheim, Hector Ramos, Iwaki, Jerry McCauley, John J. Fung, Kamada, Kissmeyer-Nielsen, Margreiter, Margreiter, McCauley, Moore, Rene J. Duquesnoy, Ron Shapiro, Starzl, Susan L. Saidman, Takaya, Takaya, Takaya, Thomas E. Starzl, Vogel, Weber   +34 more
core   +1 more source

Automatic Segmentation of Kidneys using Deep Learning for Total Kidney Volume Quantification in Autosomal Dominant Polycystic Kidney Disease

Scientific Reports, 2017
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common inherited disorder of the kidneys. It is characterized by enlargement of the kidneys caused by progressive development of renal cysts, and thus assessment of total kidney volume (TKV)
Kanishka Sharma, C. Rupprecht, A. Caroli, M. C. Aparicio, A. Remuzzi, Maximilian Baust, Nassir Navab   +6 more
semanticscholar   +1 more source

Polycystic kidney disease in a Persian cat [PDF]

, 2015
A 6-year-old intact Persian cat was presented for the primary complaint of inappetence and weight loss. Irregular surface of kidneys was palpated during physical examination. Abdominal radiograph findings were indicative of renomegaly.
Khor, Kuan Hua, Lau, Seng Fong, Phoon, Melissa Hoi Ee, Saw, Ming Hooi   +3 more
core  

A systems-biology approach to understanding the ciliopathy disorders. [PDF]

, 2011
'Ciliopathies' are an emerging class of genetic multisystemic human disorders that are caused by a multitude of largely unrelated genes that affect ciliary structure/function.
Gleeson, Joseph G, Lee, Ji Eun
core   +1 more source

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

Nature Communications, 2017
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetic cause of renal failure. Here we identify miR-17 as a target for the treatment of ADPKD. We report that miR-17 is induced in kidney cysts of mouse and human ADPKD.
Sachin S Hajarnis, R. Lakhia, Matanel Yheskel, Darren Williams, Mehran Sorourian, Xueqing Liu, Karam Aboudehen, Shanrong Zhang, Kara Kersjes, R. Galasso, Jian Li, V. Kaimal, S. Lockton, Scott Davis, Andrea Flaten, Joshua A. Johnson, W. Holland, C. Kusminski, P. Scherer, P. Harris, M. Trudel, D. Wallace, P. Igarashi, Edmund C. Lee, J. Androsavich, V. Patel   +25 more
semanticscholar   +1 more source

Androgens and Hypertension in Men and Women: a Unifying View. [PDF]

, 2017
This review was designed to revaluate the androgen role on the mechanisms of hypertension and cardiovascular risks in both men and women. Sex steroids are involved in the regulation of blood pressure, but pathophysiological mechanism is not well ...
Carmina, E. 4., Gnessi, Lucio, Lanzolla, Giulia, Moretti, Costanzo, Moretti, Marta   +4 more
core   +1 more source

Patterns of Kidney Function Decline in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Analysis From the HALT-PKD Trials.

American Journal of Kidney Diseases, 2018
BACKGROUND Previous clinical studies of autosomal dominant polycystic kidney disease (ADPKD) reported that loss of kidney function usually follows a steep and relentless course.
G. Brosnahan, Kaleab Z. Abebe, C. Moore, F. Rahbari-Oskoui, K. Bae, J. Grantham, R. Schrier, W. Braun, A. Chapman, M. Flessner, P. Harris, M. Hogan, R. Perrone, D. Miskulin, T. Steinman, V. Torres   +15 more
semanticscholar   +1 more source