Results 101 to 110 of about 1,110,820 (300)

Vascular Dysfunction, Oxidative Stress, and Inflammation in Autosomal Dominant Polycystic Kidney Disease.

American Society of Nephrology. Clinical Journal, 2018
BACKGROUND AND OBJECTIVES Both increased arterial stiffness and vascular endothelial dysfunction are evident in patients with autosomal dominant polycystic kidney disease, even early in the course of the disease when kidney function in preserved ...
Kristen L. Nowak, Wei Wang, Heather Farmer-Bailey, Berenice Y. Gitomer, Mikaela Malaczewski, J. Klawitter, A. Jovanovich, M. Chonchol   +7 more
semanticscholar   +1 more source

Renal plasticity revealed through reversal of polycystic kidney disease in mice

Nature Genetics, 2021
K. Dong, Chao Zhang, X. Tian, D. Coman, F. Hyder, Ming Ma, S. Somlo   +6 more
semanticscholar   +1 more source

Autosomal Dominant Polycystic Kidney Disease: Core Curriculum 2016.

American Journal of Kidney Diseases, 2016
Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disease. It is characterized by relentless development of kidney cysts, hypertension, and eventually end-stage renal disease (ESRD).
F. Chebib, V. Torres
semanticscholar   +1 more source

Advances in Autosomal Dominant Polycystic Kidney Disease: A Clinical Review

Kidney Medicine, 2020
Polycystic kidney disease (PKD) is a multiorgan disorder resulting in fluid-filled cyst formation in the kidneys and other systems. The replacement of kidney parenchyma with an ever-increasing volume of cysts eventually leads to kidney failure. Recently,
Niloofar Nobakht, Ramy M. Hanna, Maha Al-Baghdadi, Khalid Mohammed Ameen, Farid Arman, Ehsan Nobahkt, Mohammad Kamgar, Anjay Rastogi   +7 more
doaj  

Fetal polycystic kidney disease: Pathological overview

Journal of the Scientific Society, 2013
Polycystic kidney disease is a rare developmental anomaly inherited as autosomal dominant or autosomal recessive. It is characterized by cystic dilatation of the collecting ducts frequently associated with hepatic involvement and progression to renal ...
Sunita B Patil, Madhura D Paricharak, Deepak G Paricharak, S S More   +3 more
doaj   +1 more source

Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation [PDF]

, 2014
BACKGROUND: Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease, a cilia-associated pathology (ciliopathy).
AbouAlaiwi, Wissam A., Bacallao, Robert L., Booth, Robert L., Fruttiger, Marcus, Herbert, Britney S., Joe, Bina, Liu, Lijun, Mak, Tak W., Muntean, Brian S., Nauli, Surya M., Ratnam, Shobha, Rodriguez, Ingrid, Zhou, Jing   +12 more
core   +2 more sources

Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice

Nephrology, Dialysis and Transplantation, 2016
Recently, the European Medicines Agency approved the use of the vasopressin V2 receptor antagonist tolvaptan to slow the progression of cyst development and renal insufficiency of autosomal dominant polycystic kidney disease (ADPKD) in adult patients ...
R. Gansevoort, M. Arıcı, T. Benzing, H. Birn, G. Capasso, A. Covic, O. Devuyst, C. Drechsler, K. Eckardt, F. Emma, B. Knebelmann, Y. Le Meur, Z. Massy, A. Ong, A. Ortiz, F. Schaefer, R. Torra, R. Vanholder, A. Więcek, C. Zoccali, W. van Biesen   +20 more
semanticscholar   +1 more source

Change in kidney volume after kidney transplantation in patients with autosomal polycystic kidney disease.

PLoS ONE, 2018
BackgroundThe indication to bilateral nephrectomy in patients with autosomal dominant polycystic kidney scheduled for kidney transplantation is controversial.
Massimiliano Veroux, Cecilia Gozzo, Daniela Corona, Paolo Murabito, Daniele Carmelo Caltabiano, Luca Mammino, Alessia Giaquinta, Domenico Zerbo, Nunziata Sinagra, Pierfrancesco Veroux, Stefano Palmucci   +10 more
doaj   +1 more source

Tuberous sclerosis associated with autosomal dominant polycystic kidney disease: Case report about of the TSC2/PKD1 contiguous gene syndrome

Medicina, 2016
We present a case of a young woman with chronic kidney disease, with a history of seizures, episodes of spontaneous pneumothorax and left nephrectomy. The retrospective study of the image exams showed liver, kidney and lung cysts; in addition to cortical
Rodolfo M. Queiroz, Michela P. Gomes, Marcus V. N. Valentin, Cecília H. Miyake, Lucas G. Abud, Marcio de Castro e Silva   +5 more
doaj   +1 more source

Disease causing property analyzation of variants in 12 Chinese families with polycystic kidney disease

Molecular Genetics & Genomic Medicine, 2020
Background Polycystic kidney disease (PKD) is an inherited disease that is life‐threatening. Multiple cysts are present in the bilateral kidneys of PKD patients.
Kexian Dong, Xiaogang Liu, Xueyuan Jia, Huanhuan Miao, Wei Ji, Jie Wu, Yun Huang, Lidan Xu, Xuelong Zhang, Hui Su, Guohua Ji, Peng Liu, Rongwei Guan, Jing Bai, Songbin Fu, Xianli Zhou, Wenjing Sun   +16 more
doaj   +1 more source