Results 111 to 120 of about 82,474 (317)

Robot‐assisted vs open kidney transplantation from deceased donors

open access: yesBJU International, EarlyView.
Objectives To test the hypothesis that the type of surgical approach, robot‐assisted kidney transplantation (RAKT) vs open kidney transplantation (OKT), impacts intra‐operative and postoperative surgical outcomes of patients receiving kidney transplantation from deceased donors.
Luca Afferi   +22 more
wiley   +1 more source

Case Report: Autosomal dominant polycystic kidney disease and Wilms’ tumor in infancy and childhood

open access: yesFrontiers in Pediatrics
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is rare but one of the most common inherited kidney diseases. Normal kidney function is maintained until adulthood in most patients.
Doviltyte Zina   +9 more
doaj   +1 more source

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

open access: yesBritish Journal of Pharmacology, EarlyView.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding   +5 more
wiley   +1 more source

Rationale and design of the RESOLVE trial: lanreotide as a volume reducing treatment for polycystic livers in patients with autosomal dominant polycystic kidney disease

open access: yesBMC Nephrology, 2012
Background A large proportion of patients with autosomal dominant polycystic kidney disease (ADPKD) suffers from polycystic liver disease. Symptoms arise when liver volume increases.
Gevers Tom JG   +3 more
doaj   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan   +14 more
wiley   +1 more source

Effect of glucagon‐like peptide 1 receptor agonists on systolic blood pressure in patients with obesity, with or without diabetes: A systematic review and network meta‐analysis

open access: yesClinical Obesity, EarlyView.
Summary The effect of glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) on systolic blood pressure (SBP) in patients with obesity with or without diabetes remains unclear. The aim was to compare the effect of different drug–dose combinations of GLP‐1RAs on SBP.
Abraish Ali   +5 more
wiley   +1 more source

Caroli′s syndrome in a post renal transplant patient: Case report and review of the literature

open access: yesThe Saudi Journal of Gastroenterology, 2012
Caroli′s syndrome is characterized by bile duct ectasia in association with hepatic fibrosis. It is usually transmitted in an autosomal recessive fashion and has been well documented to be associated with autosomal recessive polycystic kidney disease and
Muhammad Z Bawany   +2 more
doaj   +1 more source

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

open access: yes, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R.   +6 more
core   +1 more source

Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy. [PDF]

open access: yes, 2020
Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential role in the regulation of salt and water homeostasis by the kidneys. V2R activation also stimulates proliferation of renal cell carcinoma (RCC) cell lines in vitro.
Calvet, James P   +10 more
core  

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