Results 11 to 20 of about 82,474 (317)

MicroRNAs and Polycystic Kidney Disease [PDF]

open access: yesKidney Medicine, 2020
Important advances have been made regarding the diagnosis and management of polycystic kidney diseases. Care of patients with polycystic kidney diseases has moved beyond supportive care for complications and chronic kidney disease to new potentially disease-modifying therapies.
Dantong Li, Liangzhong Sun
openaire   +5 more sources

Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review

open access: yesBMJ Open, 2021
Introduction Excessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical characteristics and outcomes of hyponatraemia associated with excess water intake.Methods This review was ...
Martin Howell   +11 more
doaj   +1 more source

Effect of Early and Delayed Commencement of Paricalcitol in Combination with Enalapril on the Progression of Experimental Polycystic Kidney Disease

open access: yesJournal of Cardiovascular Development and Disease, 2021
Vitamin D secosteroids are intranuclear regulators of cellular growth and suppress the renin-angiotensin system. The aim of this study was to test the hypothesis that the vitamin D receptor agonist, paricalcitol (PC), either alone or with enalapril (E ...
Priyanka S. Sagar   +4 more
doaj   +1 more source

Complications of polycystic kidney disease

open access: bronzeKidney International, 1997
A 33-year-old white man first presented to the Royal Infirmary Stirling, Scotland, 24 years ago with a history of recent-onset hematuria. Intravenous urography at that time showed a filling defect in the right kidney; a subsequent aortogram demonstrated a single simple cyst in the right kidney.
Michael L. Watson
openaire   +4 more sources

AMPK and Polycystic Kidney Disease Drug Development: An Interesting Off-Target Target

open access: yesFrontiers in Medicine, 2022
Autosomal Dominant Polycystic Kidney Disease is a genetic disease that causes dramatic perturbations of both renal tissue architecture and of a multitude of cellular signaling pathways.
Michael J. Caplan
doaj   +1 more source

Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial

open access: yesTrials, 2023
Background In autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice (BRJ) reduces blood pressure (BP) by increasing NO-mediated vasodilation. The aim of
Priyanka S. Sagar   +11 more
doaj   +1 more source

Causal relationship between polycystic ovary syndrome and chronic kidney disease: A Mendelian randomization study

open access: yesFrontiers in Endocrinology, 2023
ObjectivePolycystic ovary syndrome is one of the most common endocrine disorders among women of childbearing age. The relationship between polycystic ovary syndrome and chronic kidney disease remains unclear and controversial.
Yufei Du   +4 more
doaj   +1 more source

Atypical Polycystic Kidney Disease as defined by Imaging

open access: yesScientific Reports, 2023
Using age- and height-adjusted total kidney volume, the Mayo Clinic Imaging Classification provides a validated approach to assess the risk of chronic kidney disease (CKD) progression in autosomal dominant polycystic kidney disease (ADPKD), but requires ...
Ioan-Andrei Iliuta   +13 more
doaj   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

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