Results 61 to 70 of about 1,110,820 (300)
Polycystic horseshoe kidney [PDF]
Nephrology Dialysis Transplantation, 2006 Polycystic horseshoe kidney is thought to representtwo separate renal diseases. Horseshoe kidney is arenal fusion anomaly during embryogenesis; auto-somal dominant polycystic kidney disease (ADPKD)is a hereditary disorder due to mutations in thegenes responsible for the expression of the proteinspolycystin 1 (ADPKD1) and polycystin 2 (ADPKD2 ...
Luis Alberto Batista Peres +2 more
openaire +3 more sources
Inverting the patient involvement paradigm: defining patient led research
Research Involvement and Engagement, 2018 Plain English Summary Patients usually understand their disease and lifestyle needs better than many medical professionals. They also have important ideas about what research would be most beneficial to their lives, especially on how to manage symptoms ...
Laura B. Mader +4 more
doaj +1 more source
Distinct roles of transcription factors EGL-46 and DAF-19 in specifying the functionality of a polycystin-expressing sensory neuron necessary for C. elegans male vulva location behavior [PDF]
, 2003 Caenorhabditis elegans polycystins LOV-1 and PKD-2 are expressed in the male-specific HOB neuron, and are necessary for sensation of the hermaphrodite vulva during mating. We demonstrate that male vulva location behavior and expression of lov-1 and pkd-2
Bürglin, Thomas R. +3 more
core +1 more source
Polycystic kidney disease complicates renal pathology in a family with Fabry disease
Molecular Genetics and Metabolism Reports, 2022 Fabry disease is a rare lysosomal storage disorder that primarily affects the heart and kidneys, often presenting with reduced renal function. Polycystic kidney disease is a renal condition in which cysts are found, which have a different presentation ...
Leepakshi Johar +7 more
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Perioperative Management of Hysterectomy in a Patient with Polycystic Kidney Disease [PDF]
Journal of Clinical and Diagnostic Research, 2014 Polycystic disease of the kidney, inherited as an autosomal dominant trait is characterised by progressive expansion of numerous fluidfilled cysts resulting in massive enlargement of the kidneys ultimately resulting in kidney failure. An understanding of
Savitri. K., Ashwini. H.R., Sreedevi. S.
doaj +1 more source
Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]
, 2018 Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C +4 more
core +1 more source
American Society of Nephrology. Clinical Journal, 2019 BACKGROUND AND OBJECTIVES Microvesicles and exosomes are involved in the pathogenesis of autosomal dominant polycystic kidney disease. However, it is unclear whether they also contribute to medullary sponge kidney, a sporadic kidney malformation ...
M. Bruschi +13 more
semanticscholar +1 more source
Erythropoietin in polycystic kidneys. [PDF]
Journal of Clinical Investigation, 1989 Erythropoietin (EPO) formation in kidneys of 18 patients with autosomal dominant polycystic kidney disease (ADPKD) was investigated. In 12 patients on hemodialysis and in 6 patients with preterminal renal failure serum, EPO was 29 +/- 7 and 16 +/- 1.5 mU/ml and hemoglobin concentrations were 11.0 +/- 0.6 and 12.7 +/- 1.2 g/dl, respectively.
U Frei +9 more
openaire +2 more sources
American Society of Nephrology. Clinical Journal, 2019 BACKGROUND AND OBJECTIVES Intracranial aneurysm rupture is the most devastating complication of autosomal dominant polycystic kidney disease. Whether selective or widespread intracranial aneurysm screening is indicated remains controversial.
Irina Sanchís +10 more
semanticscholar +1 more source
Case report: Atypical polycystic kidney disease
Radiology Case Reports, 2021 Atypical or unilateral polycystic kidney disease is a rare entity that is found incidentally and is characterized on imaging as asymmetric or unilateral distribution of cysts confined to the kidneys. We present a case of an incidental finding of atypical
Christopher Shin, MD +1 more
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