Results 61 to 70 of about 82,474 (317)

A One Health overview, facilitating advances in comparative medicine and translational research. [PDF]

, 2016
Table of contentsA1 One health advances and successes in comparative medicine and translational researchCheryl StroudA2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaIgor Dmitriev, Elena Kashentseva, Jeffrey ...
Baron, David A, Bergman, Philip J, Bryan, Jeffrey N, Calvet, James P, Coates, Joan R, Cook, James L, Curiel, David T, Dmitriev, Igor, Duan, Dongsheng, Engiles, Julie B, Gandolfi, Barbara, Gaurnier-Hausser, Anita, Gnanandarajah, Josephine S, Gray, Falon, Guloy, Amado S, Harman, Robert J, Hays, Harlen D, Henry, Carolyn J, Huebner, Margie, Jacobs, Marc, Johnson, Gary S, Johnson, Gayle C, Karanu, Francis N, Kashentseva, Elena, Katz, Martin L, Laughlin, Danielle, LeBlanc, Amy K, Likins, Lee, Lyons, Leslie A, Mason, Nicola J, O'Brien, Dennis P, O'Connor, Daniel, Paterson, Yvonne, Reinero, Carol, Rindt, Hans, Robb, Edward J, Sabbagh, Ubadah, Skaff, Andrew, Stannard, James P, Stroud, Cheryl, Treml, Laura S, Wallecha, Anu, Webster, Debra A, Weiss, Mark L, Wyckoff, Gerald J   +44 more
core   +2 more sources

A Live Cell Imaging‐Compatible Bioreactor for the Interrogation of Cellular Responses to Modulated Flow Conditions

Advanced Science, EarlyView.
An open‐source, low‐cost 3D perfusion system integrating bioprinted scaffolds and live‐imaging overcomes 2D culture limitations. Modeling the cerebrospinal fluid‐filled subarachnoid space, it reveals flow‐dependent focal adhesion kinase activation in meningothelial cells, demonstrating a powerful platform for studying mechanobiology and creating ...
Subashree Srinivasan, Valerie H. Huhle, Claudia C. Bippes, Nina Tanner, Stephan Frank, Hanspeter E. Killer, Corina Kohler, Albert Neutzner   +7 more
wiley   +1 more source

An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease

Case Reports in Nephrology, 2012
Autosomal dominant polycystic kidney disease is a common hereditary disorder characterized by renal and extrarenal, cystic and noncystic manifestations. Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias,
Fausta Catapano, Stefano Pancaldi, Carlo Pace Napoleone, Lucia Barbara De Sanctis, Gaetano Gargiulo, Giuseppe Emiliani, Antonio Santoro   +6 more
doaj   +1 more source

Beyond polycystic kidney disease [PDF]

BMJ Case Reports, 2017
Tuberous sclerosis(TS) is an autosomal dominant disease caused by mutations inTSC1andTSC2genes.TSC2gene is located in chromosome 16p13.3, adjacent toPKD1gene, responsible for the autosomal dominant polycystic kidney disease. In a rare subgroup of patients, the presence of a deletion which simultaneously affects theTSC2andPKD1genes has been confirmed ...
Santos, SF, Francisco, T, Cordeiro, AI, Lopes, MJ   +3 more
openaire   +4 more sources

Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]

, 2004
Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould, Bhunia, Duyndam, Giles, Grotewold, Huan, Kim, Kimberling, Kugoh, Loghman-Adham, Löhning, Morin, Moser, Muto, Newby, Ouwens, Parnell, Peters, Pritchard, Rivat, Rodova, Saadi-Kheddouci, Scheffers, Shaulian, Smits, Sorenson, Spaargaren, Streets, Sutters, Trudel, Upadhya, van Adelsberg, van Dam, van Dam, van Dam, van Dam, van de Wetering, van de Wetering   +37 more
core   +3 more sources

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source

Coronary Artery Ectasia in a Patient with Polycystic Kidney Disease

Journal of Cardiovascular and Thoracic Research, 2011
A 44 years old male patient with acute coronary syndrome and polycystic kidney disease is described. Coronary angiography showed ectatic coronary arteries.
Leili Pourafkari, Samad Ghaffari, Bizhan Zamani, Mehdi Tolui   +3 more
doaj   +1 more source

Centrosome amplification disrupts renal development and causes cystogenesis [PDF]

, 2018
International ...
Amanda Knoten, Arquint, Astrinidis, Battini, Bettencourt-Dias, Bhaskar, Boehlke, Boletta, Brito, Brown, Burtey, Chang-Panesso, Chen, Chi, Coelho, Cosenza, Davenport, Dere, Distefano, Fisher, Ganem, Godinho, Godinho, Godinho, Goto, Habedanck, Hartman, Hendry, Hoshi, Jain, Jain, Janssen, Jinzhi Wang, Jonassen, Keefe Davis, Kobayashi, Krämer, Kulukian, Kyuhwan Shim, Lai Kuan Dionne, Levine, Lin, Ma, Mahjoub, Majumdar, Marthiens, Marthiens, Masato Hoshi, Masyuk, Moe R. Mahjoub, Mugford, Mundlos, Nano, Nigg, Nigg, Ogden, Patel, Quintyne, Renata Basto, Roselli, Saifudeen, Saifudeen, Sanjay Jain, Schmidt-Ott, Serçin, Shao, Sharma, Shillingford, Silkworth, Sillibourne, Simons, Srivastava, Takakura, Tammachote, Tao Cheng, Veronique Marthiens, Vitre, Werner, Yoder, Zhao   +79 more
core   +5 more sources

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Variable phenotype in HNF1B mutations: extrarenal manifestations distinguish affected individuals from the population with congenital anomalies of the kidney and urinary tract [PDF]

, 2019
Background: Mutations in hepatocyte nuclear factor 1B (HNF1B) have been associated with congenital anomalies of the kidney and urinary tract (CAKUT) in humans. Diabetes and other less frequent anomalies have also been described.
Aguayo Calcena, Aníbal, Ariceta, Gema, Castaño González, Luis Antonio, García Castaño, Alejandro, Madariaga Domínguez, Leire, Martínez Salazar, Rosa   +5 more
core   +2 more sources