Results 21 to 30 of about 53,957 (281)

Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial

Trials, 2023
Background In autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice (BRJ) reduces blood pressure (BP) by increasing NO-mediated vasodilation. The aim of
Priyanka S. Sagar, Alexandra Munt, Sayanthooran Saravanabavan, Farnoosh Asghar Vahedi, James Elhindi, Beatrice Nguyen, Katrina Chau, David C. Harris, Vincent Lee, Kamal Sud, Nikki Wong, Gopala K. Rangan   +11 more
doaj   +1 more source

Participant Perceptions in a Long-term Clinical Trial of Autosomal Dominant Polycystic Kidney Disease

Kidney Medicine, 2023
Rationale & Objective: The development of new therapies for autosomal dominant polycystic kidney disease requires clinical trials to be conducted efficiently. In this study, the factors affecting the recruitment and retention of participants enrolled
Sneha Amin, Irene Sangadi, Margaret Allman-Farinelli, Sunil V. Badve, Neil Boudville, Helen Coolican, Susan Coulshed, Sheryl Foster, Mangalee Fernando, Imad Haloob, David C.H. Harris, Carmel M. Hawley, Jane Holt, Martin Howell, Karthik Kumar, David W. Johnson, Vincent W. Lee, Jun Mai, Anna Rangan, Simon D. Roger, Kamal Sud, Vicente Torres, Eswari Vilayur, Gopala K. Rangan   +23 more
doaj   +1 more source

AMPK and Polycystic Kidney Disease Drug Development: An Interesting Off-Target Target

Frontiers in Medicine, 2022
Autosomal Dominant Polycystic Kidney Disease is a genetic disease that causes dramatic perturbations of both renal tissue architecture and of a multitude of cellular signaling pathways.
Michael J. Caplan
doaj   +1 more source

Germline Mutations for Kidney Volume in ADPKD

Kidney International Reports, 2022
Introduction: Valid prediction models or predictors of disease progression in children and young patients with autosomal dominant polycystic kidney disease (ADPKD) are lacking.
Hiroshi Kataoka, Rie Yoshida, Naomi Iwasa, Masayo Sato, Shun Manabe, Keiko Kawachi, Shiho Makabe, Taro Akihisa, Yusuke Ushio, Atsuko Teraoka, Ken Tsuchiya, Kosaku Nitta, Toshio Mochizuki   +12 more
doaj   +1 more source

Polycystic Kidney Disease [PDF]

Journal of the American Society of Nephrology, 2007
Renal cysts are common clinical findings, often incidentally discovered in the course of evaluating other problems. They may be either acquired or seen in association with a number of inherited and congenital disorders. The most common disorder, autosomal dominant polycystic kidney disease (ADPKD), is an important cause of end-stage renal disease (ESRD)
Peter, Igarashi, Stefan, Somlo
openaire   +2 more sources

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Polycystic kidney disease complicates renal pathology in a family with Fabry disease

Molecular Genetics and Metabolism Reports, 2022
Fabry disease is a rare lysosomal storage disorder that primarily affects the heart and kidneys, often presenting with reduced renal function. Polycystic kidney disease is a renal condition in which cysts are found, which have a different presentation ...
Leepakshi Johar, Grace Lee, Angela Martin-Rios, Kathy Hall, Cheng Cheng, Dawn Lombardo, Madeleine Pahl, Virginia Kimonis   +7 more
doaj   +1 more source

Polycystic Kidney Disease [PDF]

The Journal of Clinical Hypertension, 2005
Polycystic kidney disease, an inherited systemic disorder, is characterized by the development of multiple cysts in the kidneys and other organs. Patients can present at any age, but more often come to clinical attention (unless there is a family history) after age 30. Patients who are diagnosed before age 30 have a worse renal survival.
Pamela J, Fall, L Michael, Prisant
openaire   +2 more sources

Atypical Polycystic Kidney Disease as defined by Imaging

Scientific Reports, 2023
Using age- and height-adjusted total kidney volume, the Mayo Clinic Imaging Classification provides a validated approach to assess the risk of chronic kidney disease (CKD) progression in autosomal dominant polycystic kidney disease (ADPKD), but requires ...
Ioan-Andrei Iliuta, Aung Zaw Win, Matthew B. Lanktree, Seung Heyck Lee, Marina Pourafkari, Fatemeh Nasri, Elsa Guiard, Amirreza Haghighi, Ning He, Alistair Ingram, Crystal Quist, David Hillier, Korosh Khalili, York Pei   +13 more
doaj   +1 more source

Clinical and genetic characteristics of Korean autosomal dominant polycystic kidney disease patients [PDF]

The Korean Journal of Internal Medicine, 2021
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. It is characterized by cyst growth in the kidneys, resulting in kidney enlargement and end-stage kidney disease. The polycystic kidney disease 1 (PKD1) and
Yun Kyu Oh, Hayne Cho Park, Hyunjin Ryu, Yong-Chul Kim, Kook-Hwan Oh   +4 more
doaj   +1 more source