Results 21 to 30 of about 46,408 (230)
MicroRNAs and Polycystic Kidney Disease [PDF]
Drug Discovery Today: Disease Models, 2013 Polycystic kidney disease (PKD), the most common genetic cause of chronic renal failure, is characterized by the presence of numerous fluid-filled cysts in renal parenchyma. Despite recent progress, no FDA-approved therapy is available to retard cyst growth.
Lama, Noureddine +2 more
openaire +2 more sources
Kidney Medicine, 2019 Light chain proximal tubulopathy is a rare M-proteinemia–related nephropathy. The inclusions, composed of light chains in light chain proximal tubulopathy, are generally crystalline, and most exhibit a rhombic shape.
Ayami Ino +8 more
doaj +1 more source
Combined liver-kidney transplant in polycystic diseases: a case report [PDF]
Einstein (São Paulo), 2023 Polycystic liver disease, a hereditary pathology, usually manifests as autosomal dominant polycystic kidney disease. The many cysts in the liver cause massive hepatomegaly, majorly affecting the patient’s quality of life. In cases of refractory symptoms,
Olival Cirilo Lucena da Fonseca Neto +7 more
doaj +1 more source
Improved Structure and Function in Autosomal Recessive Polycystic Rat Kidneys with Renal Tubular Cell Therapy. [PDF]
PLoS ONE, 2015 Autosomal recessive polycystic kidney disease is a truly catastrophic monogenetic disease, causing death and end stage renal disease in neonates and children.
K J Kelly +6 more
doaj +1 more source
Molecular Mechanisms of Isolated Polycystic Liver Diseases
Frontiers in Genetics, 2022 Polycystic liver disease (PLD) is a rare autosomal dominant disorder including two genetically and clinically distinct forms: autosomal dominant polycystic kidney disease (ADPKD) and isolated polycystic liver disease (PCLD).
Ziqi Yu +5 more
doaj +1 more source
Inverting the patient involvement paradigm: defining patient led research
Research Involvement and Engagement, 2018 Plain English Summary Patients usually understand their disease and lifestyle needs better than many medical professionals. They also have important ideas about what research would be most beneficial to their lives, especially on how to manage symptoms ...
Laura B. Mader +4 more
doaj +1 more source
Surgical Management of Autosomal Dominant Polycystic Kidney Disease: Principles and Current Practice
Journal of Nepal Medical Association, 2023 Autosomal dominant polycystic kidney disease is the third most common cause of renal failure with no definitive treatment available that can directly target the development and growth of the cysts.
Badri Man Shrestha
doaj +1 more source
Emphysematous polycystic infection in a patient on peritoneal dialysis
Saudi Journal of Kidney Diseases and Transplantation, 2014 Emphysematous infection of the cysts in patients with polycystic kidney disease is very rare and seldom reported. We herein report a case of emphysematous polycystic infection in a 61-year-old male patient who was on peritoneal dialysis for end-stage ...
Shankar Prasad Nagaraju +3 more
doaj +1 more source
Journal of Medical Case Reports, 2010 Introduction Autosomal dominant polycystic kidney disease is an inherited disorder that is characterized by the development and growth of cysts in the kidneys and other organs.
Kapoor Vinay +6 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source