Results 311 to 320 of about 488,068 (360)
Some of the next articles are maybe not open access.
Reversing polycystic kidney disease
Nature Genetics, 2021A new study shows that re-expressing PKD genes early in the course of the disease can fully reverse polycystic kidney disease in mice. These results reveal an unexpected ability of the kidney to regenerate following genetic rescue of polycystin function.
openaire +2 more sources
Comprehensive Physiology, 2017
ABSTRACTRenal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling.
Joseph, Ghata, Benjamin D, Cowley
openaire +2 more sources
ABSTRACTRenal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling.
Joseph, Ghata, Benjamin D, Cowley
openaire +2 more sources
New England Journal of Medicine, 2004
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
openaire +3 more sources
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
openaire +3 more sources
InnovAiT: Education and inspiration for general practice
Polycystic kidney disease is a common inherited disorder that primarily follows an autosomal dominant inheritance pattern, leading to significant kidney problems.
Taha Alver Ansari, Zubair Ahmed Siddiqui
semanticscholar +1 more source
Polycystic kidney disease is a common inherited disorder that primarily follows an autosomal dominant inheritance pattern, leading to significant kidney problems.
Taha Alver Ansari, Zubair Ahmed Siddiqui
semanticscholar +1 more source
Neonatal Polycystic Kidney Disease
Clinics in Perinatology, 2014This article provides an up-to-date comprehensive review and summary on neonatal polycystic kidney disease (PKD) with emphasis on the differential diagnosis, clinical manifestations, diagnostic techniques, and potential therapeutic approaches for the major causes of neonatal PKD, namely hereditary disease, including autosomal recessive and autosomal ...
Priya, Verghese, Yosuke, Miyashita
openaire +2 more sources
Current Opinion in Nephrology and Hypertension, 2012
The review will examine clinically relevant advances in the area of polycystic kidney disease (PKD), mainly focusing on autosomal dominant polycystic kidney disease (ADPKD). Discussion will focus on predicting the course of ADPKD, clinical trials and new research endeavors.During the past several years PKD research has been one of the most prolific ...
openaire +3 more sources
The review will examine clinically relevant advances in the area of polycystic kidney disease (PKD), mainly focusing on autosomal dominant polycystic kidney disease (ADPKD). Discussion will focus on predicting the course of ADPKD, clinical trials and new research endeavors.During the past several years PKD research has been one of the most prolific ...
openaire +3 more sources
American Journal of Hypertension, 1996
Abstract Many inherited diseases and non-hereditary disorders have in common the development of renal cystic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation.
openaire +2 more sources
Abstract Many inherited diseases and non-hereditary disorders have in common the development of renal cystic disease. The most common, autosonal dominant polycystic kidney disease, is responsible for 5-10% of end-stage renal failure treated by dialysis or transplantation.
openaire +2 more sources
Unilateral polycystic kidney disease
Kidney International, 2021Carissa Y, Dumancas, Fouad T, Chebib
openaire +2 more sources
Autosomal dominant polycystic kidney disease.
American Family Physician, 2014A. Srivastava, Neel Patel
semanticscholar +1 more source