Results 91 to 100 of about 50,269 (316)

Medical therapy for polycystic liver disease [PDF]

The Annals of The Royal College of Surgeons of England, 2016
Introduction Somatostatin analogues and rapamycin inhibitors are two classes of drugs available for the management of polycystic liver disease but their overall impact is not clearly established. This article systematically reviews the literature on the medical management of polycystic liver disease.
S Khan, Ashley R. Dennison, G Garcea
openaire   +3 more sources

Tolvaptan for the Treatment of Enlarged Polycystic Liver Disease

Case Reports in Nephrology and Dialysis, 2017
A 44-year-old Japanese woman with autosomal dominant polycystic kidney disease was admitted to our hospital for evaluation of abdominal distension. Her eGFR was 53.7 mL/min/1.73 m2. Total kidney volume was 2,614 mL.
Hiroki Mizuno, Junichi Hoshino, Tatsuya Suwabe, Keiichi Sumida, Akinari Sekine, Yoichi Oshima, Masahiko Oguro, Kyohei Kunizawa, Masahiro Kawada, Rikako Hiramatsu, Noriko Hayami, Eiko Hasegawa, Masayuki Yamanouchi, Naoki Sawa, Kenmei Takaichi, Yoshifumi Ubara   +15 more
doaj   +1 more source

Natural progression and prediction markers in non‐clinically significant oesophageal varices in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Limited literature exists on non‐clinically significant varices (nCSV) and progression in children with portal hypertension (PHT). This study investigates trends and associations in this cohort. Methods This retrospective cohort study analysed 70 children with nCSV undergoing surveillance endoscopy between January 2012 and 2024 ...
Cody Chan, Akshat Goel, Robert Hegarty, Bethany Tucker, Vandana Jain, Eirini Kyrana, Tassos Grammatikopoulos   +6 more
wiley   +1 more source

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

Small Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou, Jingyu Yan, Chenying Cui, Yurong Xu, Kaifang Zhang, Meijun Du, Zhuowei Zhang, Xiuping Wu, Bing Li   +8 more
wiley   +1 more source

Polycystic Diseases in Visceral Organs

Obstetrics and Gynecology International, 2011
Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. Elegant studies have established the importance of ciliary structure and function in signal transduction and the sensory ...
Shakila Abdul-Majeed, Surya M. Nauli
doaj   +1 more source

Parathyroid localization [PDF]

, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B., Gutekunst, R., Hafermann, W., Kiffner, E., Löhrs, U., Scriba, Peter Christian, Thies, E., Valesky, A.   +7 more
core   +1 more source

Giant hydronephrosis: A rare cause of secondary hypertension

UroPrecision, EarlyView.
Abstract Background Hypertension secondary to giant hydronephrosis (GH) is a rare but treatable renal condition mediated by the renin‐angiotensin‐aldosterone system and tubuloglomerular feedback. In adults, GH is often diagnosed late due to nonspecific abdominal symptoms that may not manifest until advanced stages.
Ganesh Laxman Krishnamurthy, Arun Chawla, Sunil Pillai Bhaskara, Padmaraj Hegde, Ankit Agarwal, Vijay Gunashekar, Arghya Choudhuri, Aishwarya Tinaikar   +7 more
wiley   +1 more source

Polycystic liver: clinical characteristics of patients with isolated polycystic liver disease compared with patients with polycystic liver and autosomal dominant polycystic kidney disease

Liver International, 2007
AbstractAim: The goal of this study was to compare the clinical features of patients with isolated polycystic liver disease (PCLD) with those of patients with polycystic liver and autosomal dominant polycystic kidney disease (ADPKD).Methods: Cases were identified from clinical records at the University of Colorado Hospital in Denver (USA) and at the ...
Hoevenaren, I.A., Wester, R., Schrier, R.W., McFann, K., Doctor, R.B., Drenth, J.P.H., Everson, G.T.   +6 more
openaire   +3 more sources

Pkd2 dosage influences cellular repair responses following ischemia-reperfusion injury [PDF]

, 2009
Autosomal dominant polycystic kidney disease (ADPKD) results from mutations in either PKD1 or PKD2 and accounts for 10% of all patients on renal replacement therapy. The kidney disease phenotype is primarily characterized by cyst formation, but there are
Haylor, J.L., McDaid, J.P., Ong, A.C.M., Prasad, S., Tam, F.W.K.   +4 more
core   +2 more sources

Plain Language Summary of the ACCEPT Guideline for the Management of Recurrent Pregnancy Loss

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Recurrent pregnancy loss (RPL) is when a woman experiences two or more pregnancy losses. Investigating for causes of RPL can provide an explanation and possible treatment options. This is a summary of Parts 1 and 2 of Australasian Recurrent Pregnancy Loss Clinical Management Guidelines in an easy‐to‐read patient friendly format. These original
Adriana Suker, Ying Li, Anthony Marren, Danielle Robson, the Australasian CREI (Certificate of Reproductive Endocrinology and Infertility) Consensus Expert Panel on Trial evidence (ACCEPT) group   +4 more
wiley   +1 more source