Results 111 to 120 of about 5,508,271 (271)

An in vitro model of polycystic liver disease using genome-edited human inducible pluripotent stem cells

Stem Cell Research, 2018
In the developing liver, bile duct structure is formed through differentiation of hepatic progenitor cells (HPC) into cholangiocytes. A subtype of polycystic liver diseases characterized by uncontrolled expansion of bile ductal cells is caused by genetic
Akihide Kamiya, Hiromi Chikada, Kinuyo Ida, Emi Ando, Kota Tsuruya, Tatehiro Kagawa, Yutaka Inagaki   +6 more
doaj   +1 more source

Critical role of vaccination in preventing severe coronavirus disease 2019: perspectives from clinical outcomes in an Australian kidney transplant recipient cohort

Internal Medicine Journal, EarlyView.
Abstract Background Kidney transplant recipients (KTRs) disproportionately experience severe COVID‐19 infections. We previously identified concern regarding vaccine‐induced rejection as a barrier to vaccine uptake. Aim This study assesses COVID‐19 vaccine uptake, infection outcomes and allograft rejection in KTRs during the delta and omicron waves (BA ...
Dhakshayini Tharmaraj, Paayal Naidu, Mohana Baptista, Sarah McBride, Rhonda Stuart, Claire Dendle, Kevan R. Polkinghorne, William R. Mulley   +7 more
wiley   +1 more source

Polycystic Liver Disease in Autosomal Dominant Polycystic Kidney Disease

, 2016
Liver cysts are a commonly encountered phenomenon and may represent a broad cluster of disorders of diverse etiology. Most cysts are asymptomatic and do not require treatment. Simple cysts are the most prevalent.
Gradzik, Monika; Department of Radiology, Medical University of Warsaw, Niemczyk, Mariusz; Department of Immunology, Transplant Medicine and Internal Diseases, Medical University of Warsaw, Kulesza, Andrzej; Department of Immunology, Transplant Medicine and Internal Diseases, Medical University of Warsaw   +2 more
core  

Combined Liver-Kidney Transplantation in Polycystic Disease: Case Reports

, 2008
Polycystic disease causes a progressive decrease in renal function and liver degeneration. The progression of the disease evolves separately between organs and transplantation options vary: simultaneous or sequential liver-kidney transplantation or ...
ROSSI, MASSIMO, MERLI, Manuela, PUGLIESE, Francesco, FERRETTI, Stefano, D. Travaglia, SPOLETINI, GABRIELE, GINANNI CORRADINI, Stefano, LAI, QUIRINO, BERLOCO, Pasquale Bartolomeo, MENNINI, Gianluca, POLI, Luca, A. Bussotti, NOVELLI, Gilnardo   +12 more
core   +1 more source

Cumulative isotretinoin dosing, treatment response and acne relapse: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this randomized controlled trial, cumulative isotretinoin doses of 120 and 150 mg/kg showed similar relapse rates at 12 months. Both regimens achieved substantial and comparable reductions in inflammatory acne lesions across the face, chest and back.
Ruggero Cascio Ingurgio, Angela Alfano, Antonio Costanzo, Julie S. Cronk, Rebecca Cummins, Benjamin S. Daniel, Ben J. Koszegi, Linda K. Martin, Clarisse G. Mendoza, Mae Ramirez‐Quizon, Lesley M. Rhodes, Heather I. Rishel, Adam I. Rubin, Fanny Satgé, Supriya Venugopal, Anna Wilson, Dedee F. Murrell   +16 more
wiley   +1 more source

Evaluation of Liver Fibrosis in Polycystic Ovary Syndrome by Shear Wave Elastography, FIB-4 Score, and Serum Periostin Levels

Endocrinology Research and Practice, 2023
Objective: In this study, we aimed to demonstrate the presence of liver fibrosis in patients with polycystic ovary syndrome at a relatively early stage of the disease using biochemical data and 2-dimensional shear wave elastography techniques. Methods:
Eren Gürkan, Gökçen Aslan, Gülen Burakgazi, Oğuzhan Özcan   +3 more
doaj  

Naringenin inhibits the growth of Dictyostelium and MDCK-derived cysts in a polycystin-2 (TRPP2)-dependent manner. [PDF]

, 2013
Identifying and characterising potential new therapeutic agents to target cell proliferation may provide improved treatments for neoplastic disorders such as cancer and polycystic ...
Baines, D, Williams, R.S.B., Dinh, C, Ludtmann, M H R, Waheed, A., Ludtmann, M.H.R., Pakes, N, Carew, M., Williams, RS, Pakes, N., Robery, S, Carew, MA, Waheed, A, Ludtmann, MH, Kuspa, A, Robery, S., Kuspa, A., Baines, D., Carew, M A, Williams, R S, Dinh, C.   +20 more
core   +1 more source

CT-guided percutaneous aspiration and bleomycin sclerotherapy for symptomatic hepatic cysts: technique and three-year outcomes

Frontiers in Medicine
ObjectiveWe aimed to evaluate the long-term efficacy and safety of CT-guided percutaneous aspiration and bleomycin sclerotherapy for symptomatic hepatic cysts at a minimum follow-up of 3 years.Materials and methodsMedical records of patients who ...
Long Li, Long Li, Yong-Hao Lao, Yong-Hao Lao, Qiang-Lin Han   +4 more
doaj   +1 more source

Ruptured intracranial aneurysm and recessive polycystic kidney Disease: A Rare Association

Saudi Journal of Kidney Diseases and Transplantation, 2019
Autosomal recessive polycystic kidney disease (ARPKD) is the most common childhood-onset ciliopathy. Intracranial aneurysms (ICA) are a serious complication of autosomal dominant polycystic kidney disease (ADPKD).
Imed Helal, Insaf Handous, Meriam Khadhar, Hamida Bezzine, Fethi Ben Hamida, Taib Ben Abdallah   +5 more
doaj   +1 more source

Polycystic Liver Disease

International Journal of Clinical & Medical Imaging, 2016
Panel A: CT abdomen and pelvis. Pelvis B: CT abdomen and pelvis with arrows.  A 77-year-old African American male presented with intermittent abdominal pain for one week. He denied nausea, vomiting, diarrhea, constipation, fevers, anorexia, or weight loss.
openaire   +1 more source