Results 91 to 100 of about 5,508,271 (271)
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective An increasing number of women of childbearing age worldwide are using glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and are advised to use effective contraception during treatment. Nevertheless, maternity services are encountering increasing numbers of women exposed to GLP‐1 RAs shortly before conception or during pregnancy ...
Katherine G. Y. Lau +6 more
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Autosomal Dominant Polycystic Kidney Disease Induced by Ciliary Defects
, 2015 Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic renal disease, which is caused by pathogenic mutations of either PKD1 (85%) or PKD2 (15%) genes, encoding for polycystin-1 (PC1) or polycystin-2 (PC2), respectively.
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Transplant Indications in Polycystic Liver and Kidney Disease
The Turkish Journal of GastroenterologyPolycystic liver and kidney disease encompasses a spectrum of inherited disorders ,primarily autosomal dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver disease (ADPLD).
Sandra Perez-Prado, Abid Suddle
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ANZ Journal of Surgery, EarlyView.Impact of routine POOGD with routine biopsies on surgical management in 423 patients undergoing RYGB. ABSTRACT Introduction The role of routine preoperative oesophagogastroduodenoscopy (POOGD) with routine biopsies prior to Roux‐en‐Y gastric bypass (RYGB) remains controversial.
Shahab Valizadehzare, Michael Hatzifotis
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Tolvaptan for the Treatment of Enlarged Polycystic Liver Disease
Case Reports in Nephrology and Dialysis, 2017 A 44-year-old Japanese woman with autosomal dominant polycystic kidney disease was admitted to our hospital for evaluation of abdominal distension. Her eGFR was 53.7 mL/min/1.73 m2. Total kidney volume was 2,614 mL.
Hiroki Mizuno +15 more
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Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
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Genetic Predisposition of Taiwanese Patients with Polycystic Liver Disease
, 2007 在肝膽胃腸科醫師的日常工作當中，多囊性肝病的病人並不在少數，其疾病的嚴重度相差甚大，雖然大部分的肝囊腫病人都無症狀，但在某些具有較大型或較多肝囊腫的病人卻也常造成腹痛、腹脹或影響呼吸等症狀；臨床觀察上，多囊肝也有家族群聚的現象。 單純的多囊性肝病在近年來的研究當中已被認為是獨立於多囊性腎病的疾病，在白種人的研究中，體染色體PRKCSH基因突變及SEC63基因突變可在約三分之一的病人身上找到，而這兩個基因都與細胞內質網中Glucosidase II β的功能喪失有關，Glucosidase II ...
楊安民, Yang, An-Ming
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Peribiliary cysts: Two case reports
Radiology Case ReportsPeribiliary cysts are an incidental finding in patients with advanced liver disease. They were found to be common in fibrocystic disorders such as autosomal dominant polycystic kidney disease and polycystic liver disease, as well as cirrhotic livers ...
F. Oussi +8 more
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RUNX1‐Driven CPXM1 Transcription Promotes Malignant Phenotypes and EMT in Gastric Cancer Cells
Cancer Science, EarlyView.RUNX1 transcriptionally activates CPXM1, promotes EMT, and enhances the proliferation, invasion, and metastasis of gastric cancer cells. ABSTRACT Gastric cancer (GC) remains a leading cause of cancer‐related mortality worldwide, with current treatment strategies largely limited to surgery, chemotherapy, and targeted therapy.
Ping Jia +8 more
wiley +1 more source
, 2015 Polycystic kidney disease (PKD) is characterized by the presence of fluid-filled cysts in the kidneys. It is the fourth most common cause of chronic renal insufficiency or end-stage kidney disease.
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