Results 121 to 130 of about 5,508,271 (271)

Modulation of sebocyte function in acne: A pathway‐inclusive review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Acne is multifactorial, with the sebocyte acting as a central immunometabolic hub linking lipogenic, inflammatory, hormonal and barrier pathways. Mapping established and investigational therapies onto this sebocyte‐centred model offers a mechanism‐based framework that complements existing treatment paradigms and may guide more targeted, antibiotic ...
Christos C. Zouboulis   +3 more
wiley   +1 more source

Incretin‐Based Medications in Women and Reproduction: A Systematic Scoping Review and Consensus Guidelines for Clinical Practice

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Pregnancy concurrent with incretin‐based medications is contraindicated due to unknown risk of teratogenicity, as is breastfeeding. The aim of this systematic scoping review was to investigate potential risks and benefits of incretin‐based medications in relation to preconception, pregnancy, and postnatal health, and to propose ...
Kate Maslin   +19 more
wiley   +1 more source

The evolving role of liver transplantation in managing polycystic liver disease

open access: yesJournal of the Pakistan Medical Association
Polycystic liver disease (PLD) is a rare genetic condition characterised by the presence of numerous cysts throughout the liver (1). PLD was initially described in 1856 as a diseased state connected to polycystic kidney disease (PKD), and in 1925, it ...
Aqsa Afzal
doaj   +1 more source

Summarizing the Experiences of Individuals Who Have Obesity or Larger Bodies Seeking Fertility Care: A Scoping Review

open access: yesObesity Reviews, EarlyView.
ABSTRACT Females who have larger bodies or obesity may be at an increased risk for experiencing infertility. Problematically, both weight or body size and infertility are stigmatized, harming quality of care. We conducted a scoping review to understand the lived experiences of patients who may be subjected to intersecting stigmas of weight and ...
Brooke J. Hebert   +16 more
wiley   +1 more source

The Changing Landscape of Metabolic and Bariatric Surgery: Aligning Access With the Clinical Obesity Framework

open access: yesObesity Reviews, EarlyView.
ABSTRACT Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity, yet it remains profoundly underutilized. Patients seeking MBS face pretreatment requirements, including mandatory psychological evaluation, documented failed diet attempts, and months of lifestyle interventions that are substantially more extensive than ...
Francesco Saverio Papadia   +3 more
wiley   +1 more source

Clinical Effectiveness of the Recombinant Zoster Vaccine for Preventing Herpes Zoster in Individuals With Kidney Transplants: A Retrospective Cohort Study

open access: yesTransplant Infectious Disease, EarlyView.
In this retrospective cohort of kidney transplant recipients, no herpes zoster cases occurred during 398 vaccinated person‐years, compared with 78 cases (16.4 per 1000 person‐years) among unvaccinated recipients. These findings support a protective association of the recombinant zoster vaccine (RZV) and reinforce current recommendations for ...
Kyungsup Kwon   +12 more
wiley   +1 more source

Attrition and Delays in Kidney Transplant Evaluation Among People Living With HIV and End‐Stage Renal Disease

open access: yesTransplant Infectious Disease, EarlyView.
Among people living with HIV and end‐stage renal disease evaluated for kidney transplantation, most progressed successfully through evaluation and were waitlisted once engaged in the process. However, substantial delays occurred across the transplant continuum, with attrition driven primarily by incomplete testing and structural barriers rather than ...
Kyle M. Crawford   +8 more
wiley   +1 more source

Exploring lifestyle management in polycystic ovary syndrome through implementation frameworks

open access: yesExperimental Physiology, EarlyView.
Abstract Polyendocrine metabolic ovarian syndrome [PMOS; previously known as polycystic ovary syndrome (PCOS)] is an endocrine condition affecting 10%–13% of women of reproductive age, with cardiometabolic, reproductive and psychological features. The PMOS guidelines have established recommendations for its management, which can include pharmacological,
Margaret McGowan   +4 more
wiley   +1 more source

Acute hot‐water immersion augments the diastolic blood pressure nocturnal dip in healthy adults

open access: yesExperimental Physiology, EarlyView.
Abstract Hot‐water immersion (HWI) has been shown to reduce 24 h ambulatory systolic blood pressure in hypertensive adults and might represent a preventative strategy for maintaining cardiovascular health in normotensive adults. The purpose of this study was to determine the time course of post‐HWI hypotension and test the hypothesis that a single HWI ...
Samuel F. Leaney   +8 more
wiley   +1 more source

Polycystic liver disease: a clinical review

open access: yes, 2018
Polycystic liver disease rarely occurs in isolation as part of autosomal dominant polycystic liver disease, but more commonly, it exists as an extra-renal manifestation of autosomal dominant polycystic kidney disease. The pathogenesis of polycystic liver
Chandok, Natasha
core  

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