Results 211 to 220 of about 1,375,308 (279)

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

open access: yesJCPP Advances, Volume 6, Issue 3, September 2026.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista   +5 more
wiley   +1 more source

Natural Product‐Derived Vesicles in Nanotherapeutics

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley   +1 more source

Targeted metabolomics and fatty acid profiling in lean and obese polycystic ovarian syndrome patients: A pilot study. [PDF]

open access: yesEur J Obstet Gynecol Reprod Biol X
Zacharias E   +9 more
europepmc   +1 more source

European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction‐associated steatotic liver disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 555-576, September 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann   +30 more
wiley   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

open access: yesJEADV Clinical Practice, Volume 5, Issue 3, Page 912-916, September 2026.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro   +6 more
wiley   +1 more source

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