Results 61 to 70 of about 130,207 (296)

Assessment of Intestinal Hormones Cholecystokinin and Peptide YY in Iraqi Women with Polycystic Ovarian Syndrome.

مجلة كلية الطب
Background: Among the most prevalent hormonal, reproductive and metabolic issues impacting women is polycystic ovarian syndrome. Also, insulin resistance raises the chance of developing chronic illnesses in women with polycystic ovarian syndrome ...
Mariam A. Malik, Sura F. Alsaffar
doaj   +1 more source

Development of a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age

Фундаментальная и клиническая медицина, 2020
Aim. To develop the software for the diagnosis of polycystic ovary syndrome in women of early reproductive age.Material and Methods. We consecutively recruited 200 women of early reproductive age (18-35 years) with or without polycystic ovary syndrome ...
A. Yu. Beglova, S. I. Yelgina
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Variations of Steroid Hormone Metabolites in Serum and Urine in Polycystic Ovary Syndrome after Nafarelin Stimulation: Evidence for an Altered Corticoid Excretion. [PDF]

, 1995
To evaluate the clinical relevance of testing pituitary-ovarian responses in patients suffering from polycystic ovary syndrome (PCOS) with the GnRH agonist nafarelin, a 1.2-mg dose of nafarelin was given intranasally to 19 women with PCOS and 15 healthy ...
A. Lob, Burkhardt Moller, Cornelia H, Dieter Engelhardt, Karl Jacob, Michael M. Weber, Peter Luppa, Rainer Kimmig, Roger, Thomas Strowitzki   +9 more
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

The experiences of women with polycystic ovary syndrome on a very low-calorie diet [PDF]

, 2016
The research was funded by an educational grant from LighterLife. Broom was the Medical Director for LighterLife at the time of the research. Johnson is the Head of Nutrition and Research at LighterLife.
Broom, John, Johnston, Kelly L, Love, John G, McKenzie, John S, Nikokavoura, Efsevia A, Rolland, Catherine   +5 more
core   +3 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

FREQUENCY OF POLYCYSTIC OVARIAN SYNDROME IN FEMALE MEDICAL STUDENTS OF COMBINED MILITARY HOSPITAL LAHORE MEDICAL COLLEGE

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the frequency of polycystic ovarian syndrome in female medical students and the risk factors associated with polycystic ovarian syndrome. Study Design: A cross-sectional analytical study.
Maria Ahmad, Shazia Tufail, Fatima Ayub, Pakeeza Aslam, Nilofar Mustafa   +4 more
doaj  

Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome [PDF]

, 2016
© 2016 John Wiley & Sons Ltd Context: Animal studies suggest that cannabinoid receptor-1 (CB-1) blockade reduces inflammation and neovascularization by decreasing vascular endothelial growth factor (VEGF) levels associated with a reduction in ...
Atkin, Stephen L., Coady, Anne-Marie, Javed, Zeeshan, Kilpatrick, Eric S., Sathyapalan, Thozhukat   +4 more
core   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source