Results 191 to 200 of about 53,618 (254)

Natural killer cell dysregulation in polycystic ovary syndrome: immunometabolic and reproductive implication. [PDF]

Front Immunol
Jiang N, Liu J, Li C, Wang X, Pang Y, Zhang X, Ma Y, Zhang S, Xu Y, Li Q, Sun Q, Tang P, Han L.   +12 more
europepmc   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Social deprivation, race, and metabolic syndrome in patients with polycystic ovary syndrome. [PDF]

J Endocr Soc
Lee IT, King S, Sealy N, Rees J, Mumford SL, Hinkle SN, Dokras A.   +6 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Facing the diagnosis of hyperandrogenic polycystic ovary syndrome by a novel combination of circulating biomarkers. [PDF]

Sci Rep
Luque-Ramírez M, Martínez-García MÁ, Insenser M, Quintero-Tobar A, de Lope Quiñones S, Nattero-Chávez L, Quiñones-Silva J, Escobar-Morreale HF.   +7 more
europepmc   +1 more source

Cardiovascular Disease (CVD) Risk in Women With Endometriosis: A Comprehensive Meta‐Analysis

Clinical Cardiology, Volume 49, Issue 8, August 2026.
ABSTRACT Background Cardiovascular disease (CVD) remains the leading cause of mortality globally. Emerging evidence indicates that cardiovascular risk in women is frequently underestimated, underscoring the importance of recognizing sex‐specific contributors.
Maneeth Mylavarapu, Jeffry Samuel, Ravitej Thandi, Rizwan Mubashir, Vaishnavi Reddy Veeranagari, Aly Barakat, Joao Ferreira de Barros Neto, Alaa Osman, Sudeeshna Thiyagarajan, Reem Mohamed, Muhammad Junaid Hassan   +10 more
wiley   +1 more source

Exercise attenuates polycystic ovary syndrome development via improved mitochondrial proteostasis. [PDF]

Am J Physiol Endocrinol Metab
Shin C, Chen LW, Hossain MN, Li X, Islam S, Kou Z, Cui Q, de Avila JM, Zhu MJ, Du M.   +9 more
europepmc   +1 more source

Impact of Metformin Use on Clinical and Pathological Outcomes in Breast Cancer Patients With Type 2 Diabetes

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. Type 2 diabetes mellitus (T2DM) is a significant comorbidity in patients with breast cancer that negatively affects prognosis. Metformin, a first‐line antidiabetic drug, has been suggested to possess antineoplastic properties. This study
Ensiyeh Bahadoran, Monir Mirzadeh, Mohsen Jafari, Yazdan Zafari, Sahar Moghbelinejad   +4 more
wiley   +1 more source

Polyendocrine metabolic ovarian syndrome (PMOS)/polycystic ovary syndrome (PCOS): current and future trends. [PDF]

J Clin Invest
Chan JL, Masini I, Pisarska MD.
europepmc   +1 more source

Hormonal therapy and cardiovascular risk in polycystic ovary syndrome: a propensity-matched cohort study. [PDF]

Proc (Bayl Univ Med Cent)
Varma R, Ilelaboye A, Ugwuja F, Nubla A, Dispagna M, Chandi PS, Manjunath K, Philip A, Kazintet Y, Okorigba E, Akande Y.   +10 more
europepmc   +1 more source