Results 91 to 100 of about 149 (135)

On the therapy for polycystic ovary syndrome

Indian Journal of Endocrinology and Metabolism, 2017
Vittorio Unfer, Giovanni Monastra
openaire   +3 more sources

Photodynamic priming overcomes platinum resistance from short‐term exposure to select perfluoroalkyl substances in endometrial cancer cell lines

Photochemistry and Photobiology, EarlyView.
PFAS are widespread environmental contaminants that are associated with platinum resistance and mitochondrial membrane hyperpolarization in endometrial cancer cell lines. Photodynamic therapy, using BPD or ALA‐PpIX, in combination with low‐dose carboplatin overcomes PFAS‐induced platinum resistance in endometrial cancer cell lines.
Brittany P. Rickard, Lauren A. Sapienza‐Lundie, Marta Overchuk, Xianming Tan, Victoria L. Bae‐Jump, Melinda S. Yates, Suzanne E. Fenton, Imran Rizvi   +7 more
wiley   +1 more source

Weighted Cumulative Exposure Modelling to Assess the Association Between Reproductive Factors and Future Cardiovascular Disease in Women

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background The occurrence of reproductive or pregnancy events, such as severe maternal morbidity (SMM), may reveal a predisposition to chronic disease and premature mortality. However, most studies have examined these exposures without considering their timing, severity, or recurrence. Objectives We propose using a weighted cumulative exposure
Natalie Dayan, Marie‐Eve Beauchamp, Melia Alcantara, Gabriel D. Shapiro, Michal Abrahamowicz   +4 more
wiley   +1 more source

Consistency of endothelial function across two consecutive oral contraceptive pill cycles

Experimental Physiology, EarlyView.
Abstract Oral contraceptive pills (OCPs), composed of an active pill (AP; synthetic hormone) and a placebo pill (PP; synthetic hormone‐free) phase, might impact endothelial function across the OCP cycle depending on the synthetic hormone composition (type and dose).
Lindsay A. Lew, Desiree Tugwell, Tess Leavitt, Melanie Vitez, Emily J. Ferguson, Kyra E. Pyke   +5 more
wiley   +1 more source

Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐seven pre‐menopausal, untrained females performed a 12‐week resistance training programme to explore the association between androgen concentrations, androgen receptor signalling and skeletal muscle size and strength. Total testosterone was not associated with muscle mass or strength, nor with resistance training‐induced ...
Sarah E. Alexander, Briana Gatto, Olivia E. Knowles, Ross M. Williams, Kinga N. Fiebig, Paul Jansons, Paul A. Della Gatta, Andrew Garnham, Nir Eynon, Glenn D. Wadley, Brad Aisbett, Danielle Hiam, Séverine Lamon   +12 more
wiley   +1 more source

The contribution of age and sex hormones to female neuromuscular function across the adult lifespan

The Journal of Physiology, EarlyView.
Abstract figure legend This study mapped the age‐related trajectory of neuromuscular deterioration in 88 healthy females aged 18–80 years old. An accelerated reduction in neuromuscular function, primarily of peripheral muscular origin, coincided with the age of menopause onset.
Steven J. O'Bryan, Annabel Critchlow, Cas J. Fuchs, Danielle Hiam, Séverine Lamon   +4 more
wiley   +1 more source

Circulating sex hormones and volumetric breast density: A prospective study in women from the EPIC Florence cohort

International Journal of Cancer, Volume 156, Issue 12, Page 2294-2302, 15 June 2025.
What's New? Mammographic breast density is a known risk factor for breast cancer. The relationship between endogenous sex hormones and mammographic breast density remains unclear. Here, the authors evaluated prospectively the effect of circulating levels of sex hormones and sex hormone‐binding globulin on mammographic breast density in a large sample ...
Benedetta Bendinelli, Giovanna Danza, Melania Assedi, Fabio Villanelli, Giulia Vagnoni, Elisa Pastore, Calogero Saieva, Saverio Caini, Linda Vignozzi, Giovanna Masala   +9 more
wiley   +1 more source

Long Noncoding RNA NONHSAT233728.1 Promotes ROS Accumulation and Granulosa Cell Apoptosis by Regulating the MAPK/ERK1/2 Signaling Pathway

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Through isolation and transcriptomic profiling of granulosa cells, we identified the functional significance of lncRNA NONHSAT233728.1 in polycystic ovary syndrome (PCOS) pathogenesis. Knockdown of lncRNA NONHSAT233728.1 in granulosa cells elevated ROS levels, reduced the Bcl2/Bax ratio, downregulated phospho‐ERK1/2, and increased IL‐8 secretion. These
Yao Chen, Heqi Dai, Fei Mao, Yangbai Li, Ruizhi Feng, Yun Qian   +5 more
wiley   +1 more source

Comparison of Students' Attitudes and Knowledge Regarding Functional Foods in Gastronomy, Food Science, and Nutrition Programs

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Students enrolled in the functional foods course, and those from the department of Nutrition and Dietetics demonstrated a high rate of identifying both traditional and enriched foods as functional foods. The attitudes of students who enrolled in the functional foods course toward functional foods were found to be more moderate.
Şenay Burçin Alkan, Hilal Öz, Berna Madalı Kafes, Hasan Hüseyin Kara   +3 more
wiley   +1 more source

New Potential Agent in Ovarian Ischemia Reperfusion Injury: Alpha Pinene

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
The present study determined that alpha‐pinene has protective effects on ovarian ischemia‐reperfusion injury with its anti‐inflammatory, antioxidative, antiapoptotic, and autophagy inhibitory effects. It can form the basis for comprehensive studies to evaluate its potential use against ovarian ischemia‐reperfusion injury in clinical practice.
Basak Gulakar, Saime Ozbek Sebin, Esra Laloglu, Ayhan Tanyeli, Mustafa Can Güler, Elif Erbas, Serpil Can   +6 more
wiley   +1 more source