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The Lancet Diabetes & Endocrinology, 2022 Polycystic ovary syndrome (PCOS) affects 5-18% of women, and is a reproductive, metabolic, and psychological condition with impacts across the lifespan. The cause is complex, and includes genetic and epigenetic susceptibility, hypothalamic and ovarian dysfunction, excess androgen exposure, insulin resistance, and adiposity-related mechanisms. Diagnosis
Anju E, Joham +7 more
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Obstetrics & Gynecology, 2004
Women with polycystic ovarian syndrome have chronic anovulation and androgen excess not attributable to another cause. This condition occurs in approximately 4% of women. The fundamental pathophysiologic defect is unknown, but important characteristics include insulin resistance, hyperandrogenism, and altered gonadotropin dynamics.
Ertug Kovanci, John E. Buster
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Women with polycystic ovarian syndrome have chronic anovulation and androgen excess not attributable to another cause. This condition occurs in approximately 4% of women. The fundamental pathophysiologic defect is unknown, but important characteristics include insulin resistance, hyperandrogenism, and altered gonadotropin dynamics.
Ertug Kovanci, John E. Buster
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Current Opinion in Pediatrics, 1994
Polycystic ovary syndrome (PCOS) is a complex and still poorly understood process. This review examines current theories regarding the development of PCOS and focuses on the physiologic processes involved in the pubertal and adolescent period and their relationship with pathogenesis of PCOS.
S, Venturoli, E, Porcu, C, Flamigni
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Polycystic ovary syndrome (PCOS) is a complex and still poorly understood process. This review examines current theories regarding the development of PCOS and focuses on the physiologic processes involved in the pubertal and adolescent period and their relationship with pathogenesis of PCOS.
S, Venturoli, E, Porcu, C, Flamigni
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Frontiers of Medicine in China, 2010
Polycystic ovary syndrome (PCOS) is a common gynecologic endocrinopathy. The pathogenesis of PCOS is associated with both heredity and environment. PCOS has adverse impacts on female endocrine, reproduction, and metabolism. PCOS can impact women's reproductive health, leading to anovulatory infertility and higher rate of early pregnancy loss.
Zi-Jiang, Chen, Yuhua, Shi
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Polycystic ovary syndrome (PCOS) is a common gynecologic endocrinopathy. The pathogenesis of PCOS is associated with both heredity and environment. PCOS has adverse impacts on female endocrine, reproduction, and metabolism. PCOS can impact women's reproductive health, leading to anovulatory infertility and higher rate of early pregnancy loss.
Zi-Jiang, Chen, Yuhua, Shi
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Pediatric Annals, 2006
<p>Polycystic ovary syndrome (PCOS) is a heterogeneous familial disorder characterized by hyperandrogenism and chronic anovulation with onset during the peripubertal years. PCOS was initially reported in 1935 as Stein-Leventhal syndrome. Clinical features include amenorrhea, hirsutism, obesity, and enlarged polycystic ovaries.
Constance Y, Baldwin +1 more
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<p>Polycystic ovary syndrome (PCOS) is a heterogeneous familial disorder characterized by hyperandrogenism and chronic anovulation with onset during the peripubertal years. PCOS was initially reported in 1935 as Stein-Leventhal syndrome. Clinical features include amenorrhea, hirsutism, obesity, and enlarged polycystic ovaries.
Constance Y, Baldwin +1 more
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Journal of Pediatric and Adolescent Gynecology, 2003
Polycystic ovary syndrome (PCOS) is classically thought of as the triad of oligo/amenorrhea hirsutism and obesity. However it has become apparent that this disorder is heterogeneous and many subtypes exist. The basic abnormality relates to overproduction of androgens primarily from the ovary leading to the symptoms of menstrual dysfunction and ...
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Polycystic ovary syndrome (PCOS) is classically thought of as the triad of oligo/amenorrhea hirsutism and obesity. However it has become apparent that this disorder is heterogeneous and many subtypes exist. The basic abnormality relates to overproduction of androgens primarily from the ovary leading to the symptoms of menstrual dysfunction and ...
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Endocrinology and Metabolism Clinics of North America, 1997
The cardinal clinical features of PCOS are hirsutism and menstrual irregularity from anovulation. Obesity occurs in approximately 50% of hyperandrogenic anovulatory women, some of whom also have non-insulin-dependent diabetes mellitus. Underlying these clinical findings are several biochemical abnormalities, including LH hypersecretion ...
V T, Goudas, D A, Dumesic
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The cardinal clinical features of PCOS are hirsutism and menstrual irregularity from anovulation. Obesity occurs in approximately 50% of hyperandrogenic anovulatory women, some of whom also have non-insulin-dependent diabetes mellitus. Underlying these clinical findings are several biochemical abnormalities, including LH hypersecretion ...
V T, Goudas, D A, Dumesic
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Endocrinology and Metabolism Clinics of North America, 2014
Polycystic ovary syndrome (PCOS), a heterogeneous and chronic condition, today affects about 5% of women of reproductive age. PCOS is strongly associated with states of insulin resistance and hyperinsulinemia. Risk factors include genetics, metabolic profiles, and the in utero environment.
Anindita, Nandi +3 more
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Polycystic ovary syndrome (PCOS), a heterogeneous and chronic condition, today affects about 5% of women of reproductive age. PCOS is strongly associated with states of insulin resistance and hyperinsulinemia. Risk factors include genetics, metabolic profiles, and the in utero environment.
Anindita, Nandi +3 more
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Obstetrics & Gynecology, 2018
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder, representing the single most common endocrine–metabolic disorder in reproductive-aged women. Currently there are four recognized phenotypes of PCOS: 1) hyperandrogenism+oligo-anovulation+polycystic ovarian morphology; 2) hyperandrogenism+oligo-anovulation; 3) hyperandrogenism+polycystic ...
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Polycystic ovary syndrome (PCOS) is a highly prevalent disorder, representing the single most common endocrine–metabolic disorder in reproductive-aged women. Currently there are four recognized phenotypes of PCOS: 1) hyperandrogenism+oligo-anovulation+polycystic ovarian morphology; 2) hyperandrogenism+oligo-anovulation; 3) hyperandrogenism+polycystic ...
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The Journal of Pediatrics, 1993
Polycystic ovary syndrome, characterized by hyperandrogenism and menstrual irregularities, is a heterogeneous group of disorders that can disrupt normal hypothalamic-pituitary-ovarian function. Ovarian physiology is reviewed with regard to possible etiologies for excessive androgen secretion. Similar features may be present in errors in steroidogenesis,
S F, Siegel, P A, Lee
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Polycystic ovary syndrome, characterized by hyperandrogenism and menstrual irregularities, is a heterogeneous group of disorders that can disrupt normal hypothalamic-pituitary-ovarian function. Ovarian physiology is reviewed with regard to possible etiologies for excessive androgen secretion. Similar features may be present in errors in steroidogenesis,
S F, Siegel, P A, Lee
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