Results 131 to 140 of about 62,795 (319)
Cancer, 2019 Somatic mutations in hypoxia‐inducible factor 2α (HIF2A) are associated with polycythemia‐paraganglioma syndrome. Specifically, the classic presentation of female patients with recurrent paragangliomas (PGLs), polycythemia (at birth or in early childhood)
Ying Pang +14 more
semanticscholar +1 more source
International Journal of Cancer, Volume 157, Issue 3, Page 526-533, 1 August 2025.What's new? Current treatment goals for polycythemia vera, a myeloproliferative neoplasm characterized by JAK2 mutations, are mainly to prevent thrombosis. While ropeginterferon alfa‐2b treatment also reduces JAK2 mutation burden, the correlation between the hematologic and molecular responses remains to be clarified.
Seug Yun Yoon +15 more
wiley +1 more source
Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivo
Blood Cancer Journal, 2018 Polycythemia vera is characterized by the acquisition of the JAK2V617F mutation. Recommended treatments include hydroxyurea and interferon-alpha. Several groups have reported a reduction in the JAK2 mutant allele burden in interferon-treated patients ...
E. Verger +13 more
semanticscholar +1 more source
Accuracy of sonographic fetal biometry in estimating intertwin size discordance at birth
International Journal of Gynecology &Obstetrics, Volume 170, Issue 2, Page 621-631, August 2025.Abstract Objective To determine the accuracy of estimated fetal weight (EFW) and abdominal circumference (AC) discordance in diagnosing large birthweight (BW) discordance and selective fetal growth restriction (sFGR). Methods Retrospective cohort study of patients with twin pregnancies followed at a tertiary center (N = 1065).
Arietta Vayenas +2 more
wiley +1 more source
Iron stores and coagulation parameters in patients with hypoxemic polycythemia secondary to chronic obstructive pulmonary disease: the effect of phlebotomies [PDF]
, 1997 This study was designed to determine the effects of phlebotomy on iron body contents and coagulation tests of COPD patients with polycythemia secondary to hypoxemia. Seventeen patients with COPD and hematocrits higher than 54 percent (mean Hct: 57 ± 0.49
Guerra, Celso Carlos de Campos +3 more
core +2 more sources
Annals of Hematology, 2017 In patients with polycythemia vera (PV), an elevated JAK2 p.V617F allele burden is associated with indicators of more severe disease (e.g., leukocytosis, splenomegaly, and increased thrombosis risk); however, correlations between allele burden reductions
A. Vannucchi +9 more
semanticscholar +1 more source
Bleeding Complications in JAK2‐Variant Essential Thrombocythemia: A Revisit in 2025
eJHaem, Volume 6, Issue 4, August 2025.ABSTRACT Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterised by sustained thrombocytosis. Paradoxically, bleeding complications remain an under‐recognised clinical challenge. Compared with CALR‐mutated patients, those harbouring the JAK2‐V617F variant appear more prone to haemorrhage.
Gerard Gurumurthy +4 more
wiley +1 more source
The aging male: investigation, treatment and monitoring of late-onset hypogonadism in males [PDF]
, 2006 Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world. The demographics clearly demonstrate the increasing percentage of the population that is in the older age groups.
Behre, Hermann M. +11 more
core
Haematologica, 2018 Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms (MPN)[1][1] that can progress to blast phase[2][2] and to post-PV (PPV) myelofibrosis (MF) and post-ET (PET) MF,[3][3] from now on referred to as secondary ...
B. Mora +27 more
semanticscholar +1 more source