Results 111 to 120 of about 44,617 (246)
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Lentigines, café‐au‐lait macules (CALMs), and vitiligo are pigmentary disorders that seldom occur together in a single individual. Their co‐occurrence may indicate underlying genetic syndromes requiring differential diagnosis. We report an 18‐year‐old male who developed CALMs at age 11, agminated lentigines at age 13, and vitiligo on the right
Xinxin Lei, Bo Xie
wiley +1 more source
HemaSphere, Volume 10, Issue 5, May 2026.Abstract Myeloproliferative neoplasms (MPNs) are clonal disorders of hematopoietic stem cells (HSCs) that are most frequently caused by acquired somatic mutations in JAK2. A number of conditional mouse models of JAK2‐V617F‐driven MPN have been generated that rely on Cre‐LoxP‐mediated activation, resulting in polyclonal disease.
Quentin Kimmerlin +9 more
wiley +1 more source
Is altitude‐induced polycythaemia an unintended evolutionary mistake?
Experimental Physiology, EarlyView.
Peter D. Wagner, Tatum S. Simonson
wiley +1 more source
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aim Janus kinases/signal transducers and activators of transcription (JAK/STAT) pathway is crucial for various stages of immunity, from innate to adaptive responses. Type 1 IFNs activate JAK/STAT pathway by binding to receptors on JAK, phosphorylating STAT and upregulating interferon‐stimulated genes (ISGs) leading to cytokines ...
Esimebia Adjovi Amegashie +7 more
wiley +1 more source
Neutralize the neutrophils! Neutrophil β1 /β2 integrin activation contributes to JAK2-V617F–driven thrombosis [PDF]
, 2018 Barbui +4 more
core +2 more sources
Pregnancy, Volume 2, Issue 3, May 2026.Abstract Objective To establish a clinically applicable prenatal scoring system to predict perinatal loss in monochorionic diamniotic (MCDA) twins with selective fetal growth restriction (sFGR). Methods We performed a retrospective cohort study of MCDA twins with sFGR and managed expectantly at a single fetal therapy center between 2010 and 2024 ...
Shelly Soni +6 more
wiley +1 more source
Policitemia Vera en el perro : a propósito de un caso clínico [PDF]
, 1996 Se describe un caso de policitemia vera en perro. Se discute el diagnóstico diferencial del proceso, pronóstico y tramiento.A c1inical case of primary polycythemia in a dog is described.
Aceña Fabián, M. Carmen +4 more
core
Methods of Suicide Used by People With Cancer: A Scoping Review
Psycho-Oncology, Volume 35, Issue 5, May 2026.ABSTRACT Background Individuals diagnosed with cancer are at increased risk of suicide compared to the general population. Access to means is a key volitional risk factor for suicide and represents a modifiable target for prevention at a population level.
Doireann Ni Dhalaigh +5 more
wiley +1 more source
Dynamic regulation of erythropoiesis: A computer model of general applicability [PDF]
A mathematical model for the control of erythropoiesis was developed based on the balance between oxygen supply and demand at a renal oxygen detector which controls erythropoietin release and red cell production.
Leonard, J. I.
core +1 more source
Annals of Human Genetics, Volume 90, Issue 3, Page 202-214, May 2026.ABSTRACT Background and Aims Sherpa highlanders exhibit remarkable tolerance to hypoxia, most likely due to genetic adaptations shaped by natural selection at high altitude. This study examined the roles of endothelial PAS domain protein 1 (EPAS1) and egl‐9 family hypoxia‐inducible factor 1 (EGLN1) in the genetic mechanisms underlying this adaptation ...
Yunden Droma +5 more
wiley +1 more source