Results 91 to 100 of about 46,034 (246)

Ropeginterferon‐α2b in mycosis fungoides and Sézary syndrome: Safety and efficacy in 41 patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Pegylated interferon‐α2a became the off‐label alternative for treating mycosis fungoides/Sézary syndrome (MF/SS) after non‐pegylated interferons were withdrawn. This study aimed to evaluate the safety and efficacy of ropeginterferon‐α2b in MF/SS. Patients and methods We performed a retrospective multicenter analysis at
Stefanie Porkert, Juliette M. Kersten, Rosanne Ottevanger, Hanna Schratter, Regina Fink‐Puches, Van Anh Nguyen, Farzaneh Sadeghyar, Johanna Latzka, Franz Trautinger, Magdalena Hoellwerth, Peter Koelblinger, Nicole Pfannschmidt, Nina Haering, Johannes Griss, Maarten H. Vermeer, Constanze Jonak   +15 more
wiley   +1 more source

Clinical outcomes under hydroxyurea treatment in polycythemia vera: a systematic review and meta-analysis

Haematologica, 2019
Hydroxyurea is the standard treatment in high-risk patients with polycythemia vera. However, estimates of its effect in terms of clinical outcomes (thrombosis, bleeding, hematologic transformations and mortality) are lacking. We performed a meta-analysis
A. Ferrari, A. Carobbio, A. Masciulli, A. Ghirardi, G. Finazzi, V. De Stefano, A. Vannucchi, T. Barbui   +7 more
semanticscholar   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Co-occurrence of Dermatomyositis and Polycythemia Unveiling Rare de Novo Neuroendocrine Prostate Tumor

Frontiers in Oncology, 2018
We present a case of dermatomyositis together with polycythemia as initial manifestations of a particularly rare type of prostate cancer. A 69-year-old man was hospitalized for facial erythema and symptoms of fatigue.
Charalampos Papagoras, Stella Arelaki, Ioannis Botis, Ioannis Chrysafis, Stavros Giannopoulos, Panagiotis Skendros   +5 more
doaj   +1 more source

Evaluating the effect of anti–cancer nano drugs dosage and reduced leukemia and polycythemia vera levels on trend of the human blood and bone marrow cancers under synchrotron radiation

Trends in Research, 2019
Leukemia is a cancer of the blood and bone marrow; there are many types of leukemia, depending on which type of white blood cell is involved. Treatment varies with the type and stage of disease.
A. Heidari, R. Gobato
semanticscholar   +1 more source

Different Analytical Modes on Automatic Hematology Analyzers for Testing Quality Control Materials and Commutability Assessment

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Hematological disorders, critical for diagnosis, and monitoring, rely on accurate complete blood count results from automated analyzers, the reliability of which depends on robust quality control (QC). However, the ability of commutability of commercial hematology QC materials (HQCM) to behave like patient samples across different
Bingshuang Ren, Ya Cheng, Hongping Ba, Weijia Cheng, Xuwei Zhou, Hui Zhen, Shimin Wu, Jie Gong   +7 more
wiley   +1 more source

JAK2 Exon 12 Mutations in Polycythemia Vera and Idiopathic Erythrocytosis

New England Journal of Medicine, 2007
BACKGROUND The V617F mutation, which causes the substitution of phenylalanine for valine at position 617 of the Janus kinase (JAK) 2 gene (JAK2), is often present in patients with polycythemia vera, essential thrombocythemia, and idiopathic myelofibrosis.
L. M. Scott, W. Tong, Ross L. Levine, M. Scott, P. Beer, Michael R. Stratton, P. Futreal, W. Erber, M. McMullin, Claire N. Harrison, Alan J. Warren, D. Gilliland, H. Lodish, Anthony R. Green   +13 more
semanticscholar   +1 more source

Long‐term outcomes following modified Blalock–Taussig–Thomas shunt placement in 13 dogs with cyanotic congenital heart disease

Journal of Small Animal Practice, EarlyView.
Objectives To describe long‐term outcome and owner‐perceived quality of life in dogs with cyanotic congenital cardiac disease undergoing modified Blalock–Taussig–Thomas shunt procedure. Materials and Methods Medical records of dogs that underwent Blalock–Taussig–Thomas shunt between 2009 and 2025 at a small animal referral hospital were retrospectively
M. Rossanese, J. Hannabuss, D. Brockman
wiley   +1 more source

Relation of giant right atrial mass and thrombocytopenia; Recovery with surgery [PDF]

Journal of Cardiovascular and Thoracic Research
As we know, cardiac myxoma is one of the most primary cardiac masses but laboratory findings in this type of tumor is non-specific and the diagnosis is by imaging.
Roghayeh Pourkia, Sadegh Sedaghat, Hamid Reza Vafaei, Seyed Sina Taheri Otaghsare   +3 more
doaj   +1 more source