JUSTIFICATIVA E OBJETIVOS: O insulinoma é o tumor endócrino pancreático mais comum. Pode estar associado a neoplasias endócrinas múltiplas (NEM). Relatou-se o caso de paciente com distúrbios endócrinos múltiplos que, no entanto, não se enquadram em ...
Renato Toledo Maciel +2 more
doaj +1 more source
Myeloproliferative neoplasms: a review of diagnostic criteria and clinical aspects [PDF]
Chronic myeloproliferative disorders, currently called myeloproliferative neoplasms (MPN), according to the 4th edition of the World Health Organization (WHO) classification are clonal diseases of hematopoietic stem cells, in which there is increased ...
Chauffaille, Maria de Lourdes Lopes Ferrari
core +1 more source
Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats
Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North +3 more
wiley +1 more source
Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine
Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena +9 more
wiley +1 more source
Molecular mechanisms in haematological malignancies [PDF]
Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto +2 more
core
Iron stores and coagulation parameters in patients with hypoxemic polycythemia secondary to chronic obstructive pulmonary disease: the effect of phlebotomies [PDF]
This study was designed to determine the effects of phlebotomy on iron body contents and coagulation tests of COPD patients with polycythemia secondary to hypoxemia. Seventeen patients with COPD and hematocrits higher than 54 percent (mean Hct: 57 ± 0.49
Guerra, Celso Carlos de Campos +3 more
core +2 more sources
Effect of therapeutic phlebotomy on plasma volume in polycythemia patients
Background: Therapeutic phlebotomy (TP) helps in reducing the red cell mass thereby whole blood viscosity to improve tissue perfusion and oxygen delivery in polycythemia patients.
Mohandoss Murugesan +2 more
doaj +1 more source
Direct hemoglobin measurement by monolithically integrated optical beam guidance [PDF]
We present a concept for optical beam guidance by total internal reflection (TIR) at V-grooves as retro reflectors which are monolithically integrated on a microfluidic "lab-on-a-disk".
Brefka, T. +8 more
core +1 more source
Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal +11 more
wiley +1 more source
ERYTHROPOIESIS REACTION TO TUMOR GROWTH IN LUNG CANCER PATIENTS
Background. In addition to the transport of oxygen in tissues, erythrocytes participate in maintaining homeostasis therefore their qualitative and quantitative characterization may reflect a number of changes occurring in the body.
Y. A. Ragulin +8 more
doaj +1 more source

