Results 31 to 40 of about 62,795 (319)
Platelets as mediators of Thromboinflammation in chronic Myeloproliferative Neoplasms [PDF]
, 2019 Chronic myeloproliferative neoplasms (MPN) are stem cell disorders driven by mutations in JAK2, CALR, or MPL genes and characterized by myeloid proliferation and increased blood cell counts.
Heller, Paula Graciela +1 more
core +1 more source
American journal of hematology/oncology, 2018 Disease Overview: Polycythemia vera (PV) and essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding,
A. Tefferi, T. Barbui
semanticscholar +1 more source
New Perspectives on Polycythemia Vera: From Diagnosis to Therapy
International Journal of Molecular Sciences, 2020 Polycythemia vera (PV) is mainly characterized by elevated blood cell counts, thrombotic as well as hemorrhagic predisposition, a variety of symptoms, and cumulative risks of fibrotic progression and/or leukemic evolution over time.
A. Iurlo +3 more
semanticscholar +1 more source
Ultrasound in Obstetrics and Gynecology, 2020 To evaluate the long‐term neurodevelopmental and behavioral outcomes in surviving infants of pregnancies with spontaneous twin anemia–polycythemia sequence (TAPS), to compare outcome between donors and recipients, and to investigate potential risk ...
L. Tollenaar +9 more
semanticscholar +1 more source
Pediatrics and Neonatology, 2022 Background: Unlike in adults, there is no consensus on management and diagnosis of polycythemia in children. This study aims to evaluate the diagnosis and verify the algorithm in children with polycythemia.
Hatice Mine Cakmak +3 more
doaj
Polycythemia causing posterior segment vascular occlusions
Oman Journal of Ophthalmology, 2017 A 44-year-old male patient presented with features suggestive of transient central retinal artery occlusion (CRAO) followed by permanent CRAO and lateral posterior ciliary artery occlusion. He had diagnostic features of polycythemia vera (PV).
Suganeswari Ganesan +2 more
doaj +1 more source
Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study [PDF]
, 2019 Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with ...
Accurso V. +8 more
core +1 more source
Ruxolitinib versus standard therapy for the treatment of polycythemia vera.
New England Journal of Medicine, 2015 BACKGROUND Ruxolitinib, a Janus kinase (JAK) 1 and 2 inhibitor, was shown to have a clinical benefit in patients with polycythemia vera in a phase 2 study.
A. Vannucchi +16 more
semanticscholar +1 more source
Givinostat: an emerging treatment for polycythemia vera
Expert Opinion on Investigational Drugs, 2020 Introduction Polycythemia vera (PV), a Philadelphia chromosome-negative myeloproliferative neoplasm, is characterized by panmyelosis, pancytosis, and a JAK2 mutation.
H. Chifotides, P. Bose, S. Verstovsek
semanticscholar +1 more source