Results 181 to 190 of about 1,486 (206)
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Polydeoxyribonucleotide Treatment in Genital Lichen Sclerosus in Males
Urologia Internationalis, 2016It has been reported that treatment with polydeoxyribonucleotide (PDRN) in males affected by lichen sclerosus significantly improves the overall conditions of treated patients. It confirms that PDRN has a potent cytoprotective action as in other pathological conditions.
ARENA, SALVATORE, ROMEO, Carmelo
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Antibodies to DNA and a Synthetic Polydeoxyribonucleotide Produced by Oligodeoxyribonucleotides
Science, 1965Calf-thymus DNA was degraded into small fragments (oligodeoxyribonucleotides); the fragments were treated with methylated bovine serum albumin, and the complexes so formed were emulsified in complete Freund's adjuvant and injected into rabbits. The serums of the immunized rabbits contained antibodies that reacted with homologous and heterologous ...
O J, PLESCA +3 more
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Viscoelastic interactions between polydeoxyribonucleotide and ophthalmic excipients
Drug Development and Industrial Pharmacy, 2015This study investigated the interaction between polydeoxyribonucleotide (PDRN) and several ionic and nonionic isotonic agents, thickeners and a preservative that were employed as excipients in ophthalmic preparations. Interaction of each individual excipient and PDRN aqueous solution was evaluated by analyzing their rheological properties.
Iksoo, Kim +8 more
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Specificity of the Binding of fd Gene 5 Protein to Polydeoxyribonucleotides
Journal of Biomolecular Structure and Dynamics, 1989The long-wavelength circular dichroism (CD) changes induced by binding of fd gene 5 protein to the alternating DNA sequences poly[d(A-C)] and poly[d(C-T)] were similar to those induced by the protein complexed with the homopolymers poly[d(A)], poly[d(C)], and poly[d(T)]. The fd gene 5 protein showed different binding affinities for the various polymers.
Donald M Gray, D M Gray
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Adjuvant clinical effects of polydeoxyribonucleotide in lichen sclerosus
European Journal of Dermatology, 2012ejd.2012.1769 Auteur(s) : Luigi Laino laino@ifo.it Dermatological Insitute San Gallicano – IRCCS, Via Elio Chianesi 53 00144 Rome, Italy We report a group of 18 individuals (12 males, 6 females, aged 22 to 64 years) suffering from mild to severe genital lichen sclerosus (LS).
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Current Pharmaceutical Biotechnology
Introduction: In this study, a PDRN-loaded nanoliposomal (PDRN-NL) formulation, which exhibited an average particle size of 125 ± 1 nm, a polydispersity index (PDI) of 0.12 ± 0.02, a zeta potential of -52.6 ± 0.8 mV, and an encapsulation efficiency of 81.3%.
Yifan, He +4 more
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Introduction: In this study, a PDRN-loaded nanoliposomal (PDRN-NL) formulation, which exhibited an average particle size of 125 ± 1 nm, a polydispersity index (PDI) of 0.12 ± 0.02, a zeta potential of -52.6 ± 0.8 mV, and an encapsulation efficiency of 81.3%.
Yifan, He +4 more
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Effect of Polydeoxyribonucleotide Injection in a Patient With Carpal Tunnel Syndrome
American Journal of Physical Medicine & Rehabilitation, 2018Abstract Ultrasound-guided corticosteroid injection into the carpal tunnel is widely performed for the management of carpal tunnel syndrome. However, this injection may worsen the condition in patients with type 2 diabetes mellitus. Polydeoxyribonucleotide was recently recognized as a substitute for corticosteroid because of its anti ...
Jin-Sung, Park, Donghwi, Park
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Rates of heat-induced pyrimidine alterations in synthetic polydeoxyribonucleotides
Chemico-Biological Interactions, 1986Hydrolytic damages to DNA can occur at physiological conditions. The possible role of DNA conformation on the distribution of such alterations of pyrimidines was investigated. Model compounds used were the synthetic alternating copolymer poly(dG-dC):poly(dG-dC) and the homopolymer poly(dG):poly(dC).
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