Results 61 to 70 of about 16,366 (198)

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Two Patients With Extremely Long Type 1 Diabetes Duration With Very Few Complications and Remaining Insulin Secretion

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT We present two patients with > 80 years with type 1 diabetes (T1D), but with minor complications. Their history and risk factors are characterized as are factors conferring resilience against angiopathy. Amazingly, both had clearly detectable C‐peptide.
Åke Sjöholm, Daniel Espes
wiley   +1 more source

Evaluation of Urine Exosome Lecithin Cholesterol Acyltransferase as a Biomarker for Diabetes Diagnosis and Dyslipidemia

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 3, March 2026.
Integrated proteomic and model studies reveal lipid metabolism dysregulation in diabetes, detectable even in prediabetes. LCAT, a key regulator, shows compensatory upregulation during progression. The characteristic dynamics of urine exosome LCAT provide a basis for its use as a non‐invasive biomarker for early diabetic detection and disease monitoring.
Tianci Liu, Na Liu, Qian Meng, Tao Li, Man Zhang   +4 more
wiley   +1 more source

Converging neurobiological evidence in primary polydipsia resembling obsessive-compulsive disorder

Indian Journal of Psychological Medicine, 2017
Compulsive water drinking can have phenomenological and pharmacotherapeutic similarities with obsessive-compulsive disorder (OCD). Substantiating neurobiological evidence is lacking for such an association.
Karthick Subramanian, Tess Maria Rajan, Vikas Menon, Ravi Philip Rajkumar   +3 more
doaj   +1 more source

Rare Neurosarcoidosis Involvements

Respirology Case Reports, Volume 14, Issue 3, March 2026.
Neurosarcoidosis is a rare manifestation of systemic sarcoidosis. Establishing a diagnosis can be challenging for clinicians, particularly in cases of isolated neurosarcoidosis. Here, we present nine patients with rare manifestations of neurosarcoidosis. ABSTRACT Neurosarcoidosis is a rare manifestation of systemic sarcoidosis. Establishing a diagnosis
Gülce Cansu Serin, Serhat Erol, Gökhan Çelik, Özlem Özdemir Kumbasar   +3 more
wiley   +1 more source

First Case Report of Precursor‐Targeted Immune‐Mediated Anaemia in a Dog From Italy Lacking Rubriphagocytosis and With Severe Hyperferraemia: Diagnosis, Treatment, and Clinical Outcome

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
ABSTRACT Precursor‐targeted immune‐mediated anaemia (PIMA) is an uncommon and poorly understood cause of persistent non‐regenerative anaemia in dogs and cats, characterised by ineffective erythropoiesis and frequently associated with rubriphagocytosis (RP) in bone marrow samples.
Souad Nasar, Annamaria Uva, Giovanna Girardi, Giulia Tanas, Stefano Ciccarelli, Andrea Zatelli, Maria Alfonsa Cavalera, Floriana Gernone   +7 more
wiley   +1 more source

Psychogenic Polydipsia - Management Challenges.

Shanghai archives of psychiatry, 2017
Compulsive water drinking or psychogenic polydipsia is now increasingly seen in psychiatric populations. Effects of increased water intake can lead to hyponatremia causing symptoms of nausea, vomiting, seizures, delirium and can even be life threatening if not recognized and managed early.
BHATIA*, M.S., GOYAL, Aparna, SAHA, Rashmita, DOVAL, Nimisha   +3 more
openaire   +2 more sources

Rare but relevant: MDMA and hyponatraemia

Addiction, Volume 121, Issue 3, Page 713-718, March 2026.
Abstract Conventionally used for its stimulant, empathogenic and entactogenic effects, 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most commonly used psychoactive drugs, specifically among young adults and in nightlife and recreational party contexts.
Maria Rita Garcia, Nelson G. M. Gomes, Diana Dias‐da‐Silva   +2 more
wiley   +1 more source

Efficacy and Tolerability of Metyrapone in Mild Autonomous Cortisol Secretion: Real‐World Findings From Clinical Practice

Clinical Endocrinology, Volume 104, Issue 3, Page 215-221, March 2026.
ABSTRACT Objective Mild autonomous cortisol secretion (MACS) is associated with increased cardiometabolic risk factors including hypertension, type 2 diabetes and dyslipidaemia. By using evening doses of metyrapone, a short‐acting 11‐β hydroxylase inhibitor, it has been shown that it is possible to reset the abnormal circadian cortisol rhythm in MACS ...
Simon Berry, Ahmed Iqbal, John Newell‐Price, Miguel Debono   +3 more
wiley   +1 more source

Psychogenic Polydipsia: The Result, or Cause of, Deteriorating Psychotic Symptoms? A Case Report of the Consequences of Water Intoxication

Case Reports in Psychiatry, 2015
Water intoxication is a rare condition characterised by overconsumption of water. It can occur in athletes engaging in endurance sports, users of MDMA (ecstasy), and patients receiving total parenteral nutrition.
Melissa Gill, MacDara McCauley
doaj   +1 more source