Results 71 to 80 of about 16,938 (192)
British Journal of Pharmacology, Volume 183, Issue 16, Page 4919-4938, August 2026.The CLMBM nanoparticle (NP) system demonstrates strong and targeted anti‐ROS, antiapoptotic and anti‐inflammatory properties within the pancreas, thereby inhibiting the onset and progression of type 1 diabetes. Background and Purpose The destruction of β‐cells in type 1 diabetes is driven by signalling cascades that ultimately lead to cell apoptosis ...
Huiwen Pang +9 more
wiley +1 more source
Case Reports in Psychiatry, 2015 Water intoxication is a rare condition characterised by overconsumption of water. It can occur in athletes engaging in endurance sports, users of MDMA (ecstasy), and patients receiving total parenteral nutrition.
Melissa Gill, MacDara McCauley
doaj +1 more source
Swiss Medical Weekly, 2017 Primary polydipsia (PP) has been defined as excessive intake of fluids. However, the pathogenesis of PP remains unexplored. Different theories include a dysfunction in the thirst mechanism, involvement of the hippocampus, stress-reducing behaviour and ...
Clara O. Sailer +2 more
doaj +1 more source
Clinical Genetics, Volume 110, Issue 2, Page 203-209, August 2026.We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Jennifa Joseph +5 more
wiley +1 more source
Journal of Small Animal Practice, Volume 67, Issue 8, Page 680-685, August 2026.Objectives Serotonin (5‐hydroxytryptophan), implicated in a number of canine diseases, has a very short half‐life in the serum. Urine concentration of its breakdown product 5‐hydroxyindole acetic acid after an 8 hour fast is a more reliable measure of circulating serotonin in humans.
D. Castillo +3 more
wiley +1 more source
Central and nephrogenic diabetes insipidus: updates on diagnosis and management
Frontiers in EndocrinologyDiabetes insipidus (DI) is a rare endocrine disease involving antidiuretic hormone (ADH), encompassing both central and nephrogenic causes. Inability to respond to or produce ADH leads to inability of the kidneys to reabsorb water, resulting in hypotonic
Kathryn Flynn +4 more
doaj +1 more source
Case Reports in Psychiatry, 2019 Psychogenic polydipsia is one of the common cooccurrences with Schizophrenia and if not addressed can lead to fatal consequences. There are some evidences for pharmacological management of this condition but nonpharmacological management starting from ...
Pawan Sharma +3 more
doaj +1 more source
FGF-21 levels in polyuria-polydipsia syndrome
Endocrine Connections, 2018 The pathomechanism of primary polydipsia is poorly understood. Recent animal data reported a connection between fibroblast growth factor 21 (FGF-21) and elevated fluid intake independently of hormonal control by the hormone arginine-vasopressin (AVP) and
Julie Refardt +8 more
doaj +1 more source
Psychogenic polydipsia: A diagnostic challenge
Current Medicine Research and PracticePrimary polydipsia (PP) is a disorder that is clinically characterised by excessive thirst accompanied by increased fluid intake and subsequent excessive excretion of urine without an obvious cause.
Rashmi Rasi Datta +4 more
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Probable primary polydipsia in a domestic shorthair cat
Journal of Feline Medicine and Surgery Open Reports, 2015 Case summary A 10-month-old neutered male domestic shorthair cat presented with a 4 month history of polyuria and polydipsia. After a thorough diagnostic work-up the only abnormal findings were hyposthenuria and an elevated random plasma osmolality level.
Charles Tyler Long +5 more
doaj +1 more source