Results 91 to 100 of about 44,217 (244)

Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]

, 2018
In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María, González Rodríguez, María Luisa, Maestrelli, Francesca, Mura, Paola Angela, Rabasco Álvarez, Antonio María   +4 more
core   +2 more sources

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, EarlyView.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source

Nanoemulsion of Amber rice bran oil (Oryza sativa L.), characterization and properties

Tikrit Journal for Agricultural Sciences
A nanoemulsion of Iraqi Amber rice bran oil (NARBO) was prepared using an ultrasonic method. The nanoemulsions: NE1, NE2, and NE3 were formulated using an emulsifier (Tween 80 and sodium caseinate) in a ratio of 1:1 and at a concentration of (1.5, 2, 2 ...
Saif Saad Turki, Nameer Kh. Mohammed , Belal J. Muhialdin , Anis S. Hussin   +3 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Loop configuration for continuous antisolvent precipitation of lipid nanoparticles

Chemical Engineering Journal Advances
Continuous antisolvent precipitation has emerged as a scalable method for producing lipid nanoparticles (LNPs). Devices used for conducting antisolvent precipitation of LNPs are typically used in a once-through configuration.
Amol N. Joshi, Muzammilanwar S. Khan, Sarah Hudson, Vivek V. Ranade   +3 more
doaj   +1 more source

Polydisperse star polymer solutions

, 2000
We analyze the effect of polydispersity in the arm number on the effective interactions, structural correlations and the phase behavior of star polymers in a good solvent.
A. Forni, A. Jusufi, A. Jusufi, A. Sikorski, A.P. Gast, B. Duplantier, B. Duplantier, B. D’Aguanno, B. D’Aguanno, C. N. Likos, C. von Ferber, C. von Ferber, C. von Ferber, C.N. Likos, D. Richter, D. Vlassopoulos, E. Allahyarov, G. Fleischer, G. Nägele, G. Tanaka, G. Zifferer, G. Zifferer, G. Zifferer, G.A. McConnell, G.S. Grest, G.S. Grest, H. Löwen, H. Löwen, J. Batoulis, J. Batoulis, J. des Cloizeaux, J. K. G. Dhont, J. Roovers, J. Roovers, J. Roovers, J. Stellbrink, J. Stellbrink, J.-L. Barrat, J.J. Freire, K. Ishizu, K. Ohno, K. Ohno, K. Solc, K. Solc, K. Solc, K. Solc, L. Schäfer, L. Schäfer, L. Willner, L. Willner, L.-L. Zhou, M. Adam, M. Daoud, M. Watzlawek, M. Watzlawek, M. Watzlawek, M. Watzlawek, O. Jagodzinski, P. N. Pusey, P. Salgi, P.A. Nommensen, P.G. Bolhuis, P.G. Bolhuis, R. Klein, R. Seghrouchni, S. Uchida, T.A. Witten, T.A. Witten, W. Burchard, W.D. Dozier   +69 more
core   +2 more sources

Mapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS

Advanced Healthcare Materials, EarlyView.
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph, Maria Rosa Gigliobianco, Cristina Minnelli, Paolo Moretti, Francesco Spinozzi, Giovanna Mobbili, Sara Pistolesi, Cristina Casadidio, Gabriella Teti, Roberta Censi, Stefano Antonio Gattone, Piera Di Martino   +11 more
wiley   +1 more source

CHARACTERISTICS AND STABILITY ASSESSMENT OF LIPOSOMAL PREPARATIONS

Разработка и регистрация лекарственных средств, 2019
The main objective of pharmaceutical technology is to maximize the use of «pharmaceutical factors» for ensuring the high quality of prepared medicines, which coincides with the strategic task of biopharmacy, which is to maximize the effectiveness of ...
M. V. Dmitrieva, T. A. Timofeeva, N. A. Oborotova, I. I. Krasnyuk, O. I. Stepanova   +4 more
doaj  

The effect of lyophilisation on the physiochemical and biological properties of plant-based chitosan modified- poly lactic-co-glycolic acid microparticles

The Microbe
Terminalia sericea, Lantana camara, Grewiatenax, and Corchorus tridens extracts are potent against gastrointestinal bacteria. However, metabolism by gastric acid reduces their efficacy and limits their mainstream uses.
A.M. N. Shatri, Y. Lemmer, D.R. Mumbengegwi   +2 more
doaj   +1 more source