Results 11 to 20 of about 44,217 (244)
Polydispersity index from linear viscoelastic data: unimodal and bimodal linear polymer melts [PDF]
Polymer, 2003 This article describes a method for determining the polydispersity index Ip2=Mz/Mw of the molecular weight distribution (MWD) of linear polymeric materials from linear viscoelastic data. The method uses the Mellin transform of the relaxation modulus of a simple molecular rheological model.
Llorens Llacuna, Joan +2 more
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Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems [PDF]
Pharmaceutics, 2018 Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both lipophilic and hydrophilic molecules and protecting them against degradation in vitro and in vivo.
M. Danaei +7 more
openaire +4 more sources
Study and formation of vesicle systems with low polydispersity index by ultrasound method
Chemistry and Physics of Lipids, 2006 The formation of liposomes with low polydispersity index by application of ultrasounds was investigated considering methodology specifications such as sonication time and sonication power. Phosphatidylcholine (PC) liposomes were formed by the evaporation-hydration method. The vesicles were sonicated using several sonication conditions.
Pereira-Lachataignerais, J. +5 more
openaire +6 more sources
The Use of Artificial Neural Networks for Optimizing Polydispersity Index (PDI) in Nanoprecipitation Process of Acetaminophen in Microfluidic Devices [PDF]
AAPS PharmSciTech, 2012 Artificial neural networks (ANNs) were used in this study to determine factors that control the polydispersity index (PDI) in an acetaminophen nanosuspension which was prepared using nanoprecipitation in microfluidic devices. The PDI of prepared formulations was measured by dynamic light scattering.
Mahdi, Aghajani +2 more
openaire +4 more sources
Medical Sciences Forum, 2022 Melanoma is one of the most dangerous skin cancers, with a high mortality rate and an incidence that has increased radically in the past few years. This has led to a huge demand for new more effective forms of treatment.
Joana Amado +3 more
doaj +1 more source
Pharmaceutics, 2023 The current research aims to improve the solubility of the poorly soluble drug, i.e., ibuprofen, by developing self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt granulation (TSMG) approach.
Dinesh Nyavanandi +6 more
doaj +1 more source
Application of Plackett-Burman design for screening of factors affecting pitavastatin nanoparticle formulation development [PDF]
Folia Medica, 2021 Introduction: Nanoparticle formulation of pitavastatin calcium is a potential alternative to solve the solubility related problem. However, the formulation of nanoparticle involves various parameters that affect product quality.
Vinodkumar D. Ramani +2 more
doaj +3 more sources
Pharmaceutics, 2020 Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used orally to manage HIV/AIDS infection. A pseudo one-solvent bottom-up approach was used to develop and produce nano co-crystals of 3TC and AZT. Equimolar amounts of 3TC dissolved in de-ionized
Bwalya A. Witika +2 more
doaj +1 more source
Synthesis of Lipid Nanoparticles Incorporated with Ferula assa-foetida L. Extract
Cosmetics, 2022 Solid Lipid Nanoparticles (SLN) have been prepared by high-pressure homogenization and optimized in order to protect ferulic acid from Ferula assa-foetida L. extract.
Sylwia Ludek +3 more
doaj +1 more source
Study of Atom Transfer Radical Polymerization of Styrene and Its Gel Effect by Monte Carlo Simulation Method [PDF]
علوم و تکنولوژی پلیمر, 2009 Atom transfer radical polymerization (ATRP) of styrene was carried out at 105°C and a Monte Carlo simulation was employed to model the system. The variations of monomer conversion, the initiator concentration, average molecular weight, and molecular ...
M. Najafi +3 more
doaj +1 more source