Results 191 to 200 of about 70,095 (287)

Fully Synthetic, Biomimicking Polysulfates With Tunable Anticoagulant and Endothelial Cell-Selective Bioactivity. [PDF]

Macromol Biosci
Cosimi A, Pollehn R, De Martino A, Manzke S, Kerkhoff Y, Nickl P, Lohmann T, Keshi E, Lee-Thedieck C, Weinhart M.   +9 more
europepmc   +1 more source

Oppositely Charged Homopolypeptides Form Ordered Helix Assemblies With Hierarchical Structure

Small, EarlyView.
Hexagaonal and square assembly of polyarginine alfa‐helices formed in highly ordered polyarginine/polyaspartic acid complexes. The helices exhibit additional periodic staggering along their helical axis. ABSTRACT Oppositely charged polyelectrolytes are known to form polyelectrolyte complexes.
Ekaterina Buvalaia, Martin Dulle, Benoit David, Karoline Rengel, Michael Ohl, Beate Förster, Margarita Kruteva, Henrike Heise, Ralf Biehl, Holger Gohlke, Stephan Förster   +10 more
wiley   +1 more source

Design and Evaluation of Alginate-Based Hydrogels for Controlled Release of Cationic and Anionic Model Compounds. [PDF]

Gels
Mishra A, Marco KPD, Melancon MM, Bolinas DKM, Barcena AJR, Bernardino MR, Melancon MP.   +6 more
europepmc   +1 more source

Deciphering Molecular Charge Anisotropy: The Case of Antibody Solutions

Small, EarlyView.
Molecular charge anisotropy emerges as a key determinant of antibody solution behavior. A multiscale framework combining electrostatic mapping, coarse‐grained simulations, and machine‐learning‐assisted optimization identifies charge patterns that reproduce experimental structure factors and predict collective properties across concentration, revealing ...
Fabrizio Camerin, Susana Marín‐Aguilar, Anna Stradner, Peter Schurtenberger, Emanuela Zaccarelli   +4 more
wiley   +1 more source

Tunable Surface Nanotopography with Disordered Hyperuniformity in Poly(ethylenimine)/Alginate-Based Multilayered Films. [PDF]

ACS Appl Mater Interfaces
Nayan MNIS, Kashem MNH, Shi W, Joshi R, Jiao Y, Nam S, Li W.   +6 more
europepmc   +1 more source

Engineering Protein‐Polymer Hybrid Multilayer Microreactors as Antioxidant and Anti‐Inflammatory Therapeutics: Effect of Single Enzyme Nanogel Localization Within the Multilayer Systems

Small, EarlyView.
Protein‐based multilayer microreactors combine single‐enzyme nanogels (SENs) and layer‐by‐layer (LbL) assembly to control catalase localization. Positioning the enzyme within the core or at different locations of the multilayer architecture reveals how spatial organization influences antioxidant and anti‐inflammatory activity.
Maria A. Motta, Sergio Martin‐Saldaña, Daniel Sánchez‐deAlcázar, Ana Beloqui, Marcelo Calderón, Aitor Larrañaga   +5 more
wiley   +1 more source

Data Interpretation Paradoxes in a Nanoencapsulated α-Mangostin Hydrogel Film for Anti-Acne Therapy [Response to Letter]. [PDF]

Drug Des Devel Ther
Yuniarsih N, Chaerunisaa AY, Mohammed AFA, Elamin KM, Muchtaridi M, Wathoni N.   +5 more
europepmc   +1 more source

Patterning of Artificial Cell Populations Via Laser Induced Forward Transfer for Controlled and Localized Cargo Uptake and Release

Small, EarlyView.
Polypeptide‐based complex coacervate artificial cells were prepared in situ within a viscoelastic matrix and adhered to the biomaterial ink, which was subsequently LIFT‐printed. The artificial cells preserved their structural stability during printing and retained biologically relevant properties, showing controlled cargo uptake and release ...
Yiğitcan Sümbelli, Núria Ginés Rodriguez, Lars J. M. M. Paffen, Arjan Hazegh Nikroo, Riccardo Levato, Jan C. M. van Hest, Jos Malda   +6 more
wiley   +1 more source

Decoding Cytoskeletal Mechanobiology with Tunable Microenvironments. [PDF]

ACS Biomater Sci Eng
Kandel R, Chowdhury MAH, Robinson J, Reinemann DN.   +3 more
europepmc   +1 more source

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

Smart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source