Results 211 to 220 of about 93,513 (258)
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
BMEMat, EarlyView.A multifunctional nanomedicine is designed to engineer NK cells for enhanced cancer immunotherapy through perforation and desialylation, enabling real‐time monitoring of ATP and GrB levels for precise efficacy assessment. Abstract Efficient enhanced NK cell therapy is of critical importance in the immune treatment of cancer.
Yuanjiao Yang +8 more
wiley +1 more source
BMEMat, EarlyView.Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu +7 more
wiley +1 more source
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Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
Expert Opinion on Drug Delivery, 2016Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development.The unique properties and applications of PEG have been discussed at length in ...
Ranjita Shegokar, Anisha D'Souza
exaly +3 more sources
Control of silk microsphere formation using polyethylene glycol (PEG)
Acta Biomaterialia, 2016A one step, rapid method to prepare silk microspheres was developed, with particle size controlled by the addition of polyethylene glycol (PEG). PEG molecular weight (4.0K-20.0KDa) and concentration (20-50wt%), as well as silk concentration (5-20wt%), were key factors that determined particle sizes varying in a range of 1-100μm. Addition of methanol to
Zhaozhu Zheng, Gang Li, David Kaplan
exaly +3 more sources
International Journal of Pharmaceutics, 2002
The effect of spray drying polyethylene glycol (PEG) 4000 and lactose/PEG solutions was investigated. Micro-spherical PEG particles were successfully prepared from ethanol, which allowed lower outlet temperatures than water. The product was crystalline and consisted of rough spheres or rod like particles.
Anne Marie Healy, Owen I Corrigan
exaly +3 more sources
The effect of spray drying polyethylene glycol (PEG) 4000 and lactose/PEG solutions was investigated. Micro-spherical PEG particles were successfully prepared from ethanol, which allowed lower outlet temperatures than water. The product was crystalline and consisted of rough spheres or rod like particles.
Anne Marie Healy, Owen I Corrigan
exaly +3 more sources
Absorption of Polyethylene Glycol (PEG) Polymers: The Effect of PEG Size on Permeability
Journal of Pharmaceutical Sciences, 2009Polyethylene glycol (PEG) polymers are large amphiphilic molecules that are highly hydrated in solution. To explore the permeability properties of different sized PEG polymers across epithelial membranes in vivo, we examined the absorption of fluorescently labeled PEG conjugates sized 0.55-20 kDa from the lung, since this system provides a reservoir ...
Hema, Gursahani +4 more
openaire +2 more sources
Polyethylene Glycols (PEG) and Related Structures
A & A Case Reports, 2015We describe hypersensitivity to polyethylene glycols (PEGs), with cross-reactivity to a structural analog, polysorbate 80, in a 69-year-old patient with perioperative anaphylaxis and subsequent, severe anaphylactic reactions to unrelated medical products.
Emily, Wenande +3 more
openaire +2 more sources
Studies on antigenicity of the polyethylene glycol (PEG)-modified uricase
International Journal of Immunopharmacology, 1985The purified uricase (urate: oxygen oxidoreductase, EC 1.7.3.3) from Candida utilis was modified to varying degrees with monomethoxypolyethylene glycol (PEG) of different molecular weights using cyanuric chloride as the coupling reagent. The PEG-uricase conjugates were examined on their immunological properties by means of ring test and passive ...
J, Tsuji +4 more
openaire +2 more sources