Results 241 to 250 of about 40,214 (287)

Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect

Journal of Child Psychology and Psychiatry, EarlyView.
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson, Hanna R. Wright, Jorden E. Jacinto Schreeder, Joel T. Nigg, Elinor L. Sullivan   +4 more
wiley   +1 more source

Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis

Journal of Child Psychology and Psychiatry, EarlyView.
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang, L. Rodrigo Patino, Wenjing Zhang, Su Lui, Melissa P. DelBello, Robert K. McNamara   +5 more
wiley   +1 more source

Development of a polygenic score predicting drug resistance and patient outcome in breast cancer. [PDF]

NPJ Precis Oncol
Sahu D, Shi J, Segura Rueda IA, Chatrath A, Dutta A.   +4 more
europepmc   +1 more source

Individual differences in effects of stressful life events on childhood ADHD: genetic, neural, and familial contributions

Journal of Child Psychology and Psychiatry, EarlyView.
Background This study elucidates the intricate relationship between stressful life events and the development of ADHD symptoms in children, acknowledging the considerable variability in individual responses. By examining these differences, we aim to uncover the unique combinations of factors contributing to varying levels of vulnerability and ...
Seung Yun Choi, Jinwoo Lee, Junghoon Park, Eunji Lee, Bo‐Gyeom Kim, Gakyung Kim, Yoonjung Yoonie Joo, Jiook Cha   +7 more
wiley   +1 more source

Enhancing the Polygenic Score Catalog with tools for score calculation and ancestry normalization. [PDF]

Nat Genet
Lambert SA, Wingfield B, Gibson JT, Gil L, Ramachandran S, Yvon F, Saverimuttu S, Tinsley E, Lewis E, Ritchie SC, Wu J, Cánovas R, McMahon A, Harris LW, Parkinson H, Inouye M.   +15 more
europepmc   +1 more source

Multivariate maternal effects across the internalizing–externalizing spectrum in childhood: results from the Norwegian mother, father, and child cohort study

Journal of Child Psychology and Psychiatry, EarlyView.
Background From a functionalist perspective, parenting behaviors have adaptive functions and are partly expressions of genetic variation. Maternal genes that have effects on children are often referred to as indirect maternal genetic effects. Indirect genetic effects provide a means for measuring the role of parenting without the need for specifying ...
Espen Moen Eilertsen, Nikolai Haahjem Eftedal, Rosa Cheesman, Ziada Ayorech, Joakim Coleman Ebeltoft, Hans Fredrik Sunde, Anneli Desiré Tandberg, Fartein Ask Torvik, Eivind Ystrom   +8 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Association of centenarian polygenic score with disability-free survival and its modification effects on aging outcomes

Sasaki T, Tadaka S, Hirata T, Nishimoto Y, Shikimoto R, Abe Y, Shiohama A, Shirota M, Motoike I, Tamiya G, Kinoshita K, Yamamoto M, Latysheva N, Ledsam J, Kayama H, Momozawa Y, Kubo M, Nakatani E, Inoue I, Ikeuchi T, Mori H, Takebayashi T, Okano H, Suematsu M, Kosaki K, Hirose N, Arai Y.   +26 more
europepmc   +1 more source

The maize mitogen‐activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance

New Phytologist, EarlyView.
Summary Southern leaf blight (SLB), caused by the necrotrophic fungus Cochliobolus heterostrophus, is a major foliar disease of maize (Zea mays) world‐wide. A genome‐wide association study was performed to dissect the genetic basis of SLB resistance in maize. Functional validation was performed using mutant and transgenic analyses.
Tao Zhong, Bode Olukolu, Yang Bian, Shang Xue, Randall J. Wisser, Peter S. Ojiambo, James B. Holland, Qin Yang, Peter Balint‐Kurti   +8 more
wiley   +1 more source

Shared Genetic Links Between Sleep, Neurodevelopmental and Neuropsychiatric Conditions: A Genome-Wide and Pathway-Based Polygenic Score Analysis. [PDF]

Genes Brain Behav
Fahey L, Lopez LM.
europepmc   +1 more source