Results 251 to 260 of about 2,929,620 (353)

MS29.03 Polygenic Risk Score for Risk Assessment [PDF]

, 2018
Rayjean J. Hung, Yonathan Brhane, Nithiananda Chatterjie, David C. Christiani, N. Caporaso, M. Landi, Loı̈c Le Marchand, Geoffrey Liu, Simon Lam, John K. Field, Paul Brennan, Christopher I. Amos   +11 more
openalex   +1 more source

Polygenic Risk Scores in Familial Hypercholesterolemia

Journal of the American College of Cardiology, 2019
Daniel J. Rader, Samip Sheth
openaire   +3 more sources

Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification. [PDF]

Alzheimers Dement
D'Aoust T, Clocchiatti-Tuozzo S, Rivier CA, Mishra A, Hachiya T, Grenier-Boley B, Soumaré A, Duperron MG, Le Grand Q, Bouteloup V, Proust-Lima C, Samieri C, Neuffer J, Sargurupremraj M, Chêne G, Helmer C, Thibault M, Amouyel P, Lambert JC, Kamatani Y, Jacqmin-Gadda H, Tregouët DA, Inouye M, Dufouil C, Falcone GJ, Debette S.   +25 more
europepmc   +1 more source

Genetic and non‐genetic factors influencing KLH binding natural antibodies and specific antibody response to Newcastle disease in Kenyan chicken populations

Journal of Animal Breeding and Genetics, Volume 140, Issue 1, Page 106-120, January 2023., 2023
Abstract This study aimed at investigating the influence of genetic and non‐genetic factors on immune traits to inform on possibilities of genetic improvement of disease resistance traits in local chicken of Kenya. Immune traits such as natural and specific antibodies are considered suitable indicators of an individual's health status and consequently,
Sophie Miyumo, Chrilukovian B. Wasike, Evans D. Ilatsia, Jörn Bennewitz, Mizeck G. Chagunda   +4 more
wiley   +1 more source

Risk factors affecting polygenic score performance across diverse cohorts. [PDF]

Elife
Hui D, Dudek S, Kiryluk K, Walunas TL, Kullo IJ, Wei WQ, Tiwari H, Peterson JF, Chung WK, Davis BH, Khan A, Kottyan LC, Limdi NA, Feng Q, Puckelwartz MJ, Weng C, Smith JL, Karlson EW, Regeneron Genetics Center, Penn Medicine BioBank, Jarvik GP, Ritchie MD.   +21 more
europepmc   +1 more source

Clinical Relevance of Genome-Wide Polygenic Score may Be Less than Claimed

, 2018
David Curtis
openalex   +2 more sources

A polygenic score for height identifies an unmeasured genetic predisposition among pediatric patients with idiopathic short stature. [PDF]

Genome Med
Shelley JP, Shi M, Peterson JF, Van Driest SL, Simmons JH, Mosley JD.   +5 more
europepmc   +1 more source

Drinking motives and alcohol sensitivity mediate multidimensional genetic influences on alcohol use behaviors

Alcohol, Clinical and Experimental Research, EarlyView.
Alcohol use behaviors (AUBs) are heritable, and research has identified many regions of the genome that correlate with individual differences in AUBs. However, there are many steps between DNA and behavior where these genes could have an effect. Here, we tested whether genes are associated with AUBs via intermediate measures of personality, alcohol ...
Jeanne E. Savage, Spit for Science Working Group, Karen Chartier, Ananda Amstadter, Emily Lilley, Renolda Gelzinis, Anne Morris, Katie Bountress, Amy E. Adkins, Nathaniel Thomas, Zoe Neale, Kimberly Pedersen, Thomas Bannard, Seung B. Cho, Peter Barr, Holly Byers, Erin C. Berenz, Erin Caraway, Seung B. Cho, James S. Clifford, Megan Cooke, Elizabeth Do, Alexis C. Edwards, Neeru Goyal, Laura M. Hack, Lisa J. Halberstadt, Sage Hawn, Sally Kuo, Emily Lasko, Jennifer Lend, Mackenzie Lind, Elizabeth Long, Alexandra Martelli, Jacquelyn L. Meyers, Kerry Mitchell, Ashlee Moore, Arden Moscati, Aashir Nasim, Jill Opalesky, Cassie Overstreet, A. Christian Pais, Tarah Raldiris, Jessica Salvatore, Rebecca Smith, David Sosnowski, Jinni Su, Chloe Walker, Marcie Walsh, Teresa Willoughby, Madison Woodroof, Jia Yan, Cuie Sun, Brandon Wormley, Brien Riley, Fazil Aliev, Roseann Peterson, Bradley T. Webb, Danielle M. Dick, Danielle Posthuma   +58 more
wiley   +1 more source

A machine-learning heuristic to improve gene score prediction of polygenic traits Short title: Machine-learning boosted gene scores [PDF]

, 2017
Guillaume Paré, Shihong Mao, Wei Q. Deng   +2 more
openalex  

Use of an Alzheimer’s disease polygenic risk score to identify mild cognitive impairment in adults in their 50s

, 2018
Mark W. Logue, Matthew S. Panizzon, Jeremy A. Elman, Nathan A. Gillespie, Sean N. Hatton, Daniel E. Gustavson, Ole A. Andreassen, Anders M. Dale, Carol E. Franz, Michael J. Lyons, Michael C. Neale, Chandra A. Reynolds, Xin Tu, William S. Kremen   +13 more
openalex   +2 more sources